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Cardiopulmonary Bypass Priming Using Autologous Cord Blood in Neonatal Congenital Cardiac Surgery

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Author(s)
Eun Seok ChoiSungkyu ChoWoo Sung JangWoong-Han Kim
Keimyung Author(s)
Jang, Woo Sung
Department
Dept. of Thoracic & Cardiovascular Surgery (흉부외과학)
Journal Title
Korean Circulation Journal
Issued Date
2016
Volume
46
Issue
5
Keyword
Fetal bloodCardiopulmonary bypassCardiac surgery
Abstract
Background and Objectives: A blood transfusion is almost inevitable in neonatal cardiac surgery. This study aimed to assess the feasibility
of using autologous cord blood for a cardiopulmonary bypass (CPB) priming as an alternative to an allo-transfusion in neonatal cardiac
surgery.
Subjects and Methods: From January 2012 to December 2014, cord blood had been collected during delivery after informed consent and
was stored immediately into a blood bank. Eight neonatal patients had their own cord blood used for CPB priming during cardiac surgery.
Results: All patients underwent surgery for their complex congenital heart disease. The median age and body weight at surgery was 11
days (from 0 to 21 days) and 3.2 kg (from 2.2 to 3.7 kg). The median amount and hematocrit of collected cord blood was 72.5 mL (from
43 to 105 mL) and 48.7% (from 32.0 to 51.2%). The median preoperative hematocrit of neonates was 36.5% (from 31.0 to 45.0%); the
median volume of CPB priming was 130 mL (From 120 to 140 mL). Seven out of eight patients did not need an allo-transfusion in CPB
priming and only one neonate used 20 mL of packed red blood cells in CPB priming to obtain the target hematocrit.
Conclusion: Autologous cord blood can be used for CPB priming as alternative to packed red blood cells in neonatal congenital cardiac
surgery in order to reduce allo-transfusion.
Keimyung Author(s)(Kor)
장우성
Publisher
School of Medicine
Citation
Eun Seok Choi et al. (2016). Cardiopulmonary Bypass Priming Using Autologous Cord Blood in Neonatal Congenital Cardiac Surgery. Korean Circulation Journal, 46(5), 714–718. doi: 10.4070/kcj.2016.46.5.714
Type
Article
ISSN
1738-5520
DOI
10.4070/kcj.2016.46.5.714
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32486
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Thoracic & Cardiovascular Surgery (흉부외과학)
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