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Anatomical resection of hepatocellular carcinoma: A critical review of the procedure and its benefits on survival

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Author(s)
Koo Jeong KangKeun Soo Ahn
Keimyung Author(s)
Kang, Koo JeongAhn, Keun Soo
Department
Dept. of Surgery (외과학)
Journal Title
World Journal of Gastroenterology
Issued Date
2017
Volume
23
Issue
7
Keyword
Hepatocellular carcinomaCirrhosisCurativeAnatomical resectionPrognosis
Abstract
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer and the third most frequent cause of cancer-related death. Advances in preoperative assessment of HCC (e.g., imaging studies and liver function tests), surgical techniques, and postoperative care have improved the surgical outcomes and survival of patients who undergo hepatic resection for HCC. However, in the last 20 years, the long-term survival after hepatectomy has remained unsatisfactory owing to the high rates of local recurrence and multicentric occurrence. Anatomical liver resection (AR) was introduced in the 1980s. Although several studies have revealed tangible benefits of AR for HCC, these benefits are still debated. Because most HCCs occur in patients with liver cirrhosis and poor hepatic function, there are many factors that affect survival, including the surgical method. Nevertheless, many studies have documented the perioperative and long-term benefits of AR in various conditions. In this article, we review the results of several recently published, well-designed comparative studies of AR, to investigate whether AR provides real benefits on survival outcomes. We also discuss the potential pitfalls associated with this approach.
Keimyung Author(s)(Kor)
안근수
강구정
Publisher
School of Medicine
Citation
Koo Jeong Kang and Keun Soo Ahn. (2017). Anatomical resection of hepatocellular carcinoma: A critical review of the procedure and its benefits on survival. World Journal of Gastroenterology, 23(7), 1139–1146. doi: 10.3748/wjg.v23.i7.1139
Type
Article
ISSN
1007-9327
DOI
10.3748/wjg.v23.i7.1139
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32586
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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