Long-Term Prognosis of Patients with an Implantable Cardioverter-Defibrillator in Korea.
- Author(s)
- Jae-Sun Uhm; Tae-Hoon Kim; In-Cheol Kim; Young-Ah Park; Dong Geum Shin; Yeong-Min Lim; Hee-Tae Yu; Pil-Sung Yang; Hui-Nam Pak; Seok-Min Kang; Moon-Hyoung Lee; Boyoung Joung
- Keimyung Author(s)
- Kim, In Cheol
- Department
- Dept. of Internal Medicine (내과학)
- Journal Title
- Yonsei Medical Journal
- Issued Date
- 2017
- Volume
- 58
- Issue
- 3
- Keyword
- Heart failure; implantable cardioverter-defibrillator; primary prevention; sudden cardiac death
- Abstract
- Purpose: The objective of this study was to elucidate the long-term prognosis of patients with implantable cardioverter-defibrillators
(ICDs) in Korea.
Materials and Methods: We enrolled 405 patients (age, 57.7±16.7 years; 311 men) who had undergone ICD implantation. The
patients were divided into three groups: heart failure (HF) and ICD for primary (group 1, n=118) and secondary prevention
(group 2, n=93) and non-HF (group 3, n=194). We compared appropriate and inappropriate ICD therapy delivery among the
groups and between high- (heart rate ≥200 /min) and low-rate (<200 /min) ICD therapy zones.
Results: During the follow-up period (58.9±49.8 months), the annual appropriate ICD therapy rate was higher in group 2 (10.4%)
than in groups 1 and 3 (6.1% and 5.9%, respectively, p<0.001). There were no significant differences in annual inappropriate ICD
therapy rate among the three groups. In group 1, the annual appropriate ICD therapy rate was significantly lower in patients with
a high-rate versus a low-rate therapy zone (4.5% and 9.6%, respectively, p=0.026). In group 3, the annual inappropriate ICD therapy
rate was significantly lower in patients with a high-rate versus a low-rate therapy zone (3.1% and 4.0%, respectively, p=0.048).
Conclusion: Appropriate ICD therapy rates are not low in Korean patients with ICD, relative to prior large-scale studies in Western
countries. Appropriate and inappropriate ICD therapy could be reduced by a high-rate therapy zone in patients with HF and
ICD for primary prevention, as well as non-HF patients, respectively.
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