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Prospective Validation of Objective Prognostic Score for Advanced Cancer Inpatients in South Korea: A Multicenter Study

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Author(s)
Yoon Seok JoonSuh Sang-YeonLee Yong JooPark JeannoHwang SunwookLee Sanghee ShinyAhn Hong YupKoh Su-JinPark Keon Uk
Keimyung Author(s)
Park, Keon Uk
Department
Dept. of Internal Medicine (내과학)
Journal Title
Journal of Palliative Medicine
Issued Date
2017
Volume
20
Issue
1
Keyword
cancerpalliative careprognostic scoresurvivalvalidation
Abstract
Background: Objective Prognostic Score (OPS) was developed as an easy and simple prognosticating tool in South Korea. It has been validated retrospectively in a single center in South Korea.

Objective: We aimed to validate the OPS prospectively for advanced cancer inpatients in South Korea using a multicenter study.

Design: This was a prospective cohort study.

Setting/Subjects: We enrolled 243 advanced cancer patients admitted in five palliative care units in South Korea from May 2013 till March 2015. Seven members of the Korean Palliative Medicine Research Network who are experts of palliative care led the study.

Measurements: Clinical variables (dyspnea/anorexia/performance status) and laboratory variables (total leukocyte counts/serum total bilirubin/serum creatinine/lactate dehydrogenase) were collected at the enrollment. Survival time was calculated as days from enrollment to death during admission.

Results: A total of 217 patients were included in the final analysis (feasibility: 89.3%). Survival time of the higher OPS group (OPS ≥3) and the lower OPS group (OPS <3) was 10.0 (95% confidence interval (CI) 7.72–12.28) days and 32.0 (95% CI 25.44–38.56) days, respectively. There were significant differences between the 2 groups (p < 0.001). Overall accuracy of OPS ≥3 for predicting survival less than three weeks was 71.0%.

Conclusions: OPS was successfully validated using a prospective multicenter study in South Korea. It is a useful method to predict three-week survival of Korean inpatients with advanced cancer.
Keimyung Author(s)(Kor)
박건욱
Publisher
School of Medicine
Citation
Yoon Seok Joon et al. (2017). Prospective Validation of Objective Prognostic Score for Advanced Cancer Inpatients in South Korea: A Multicenter Study. Journal of Palliative Medicine, 20(1), 65–68. doi: 10.1089/jpm.2016.0044
Type
Article
ISSN
1096-6218
Source
https://www.liebertpub.com/doi/10.1089/jpm.2016.0044
DOI
10.1089/jpm.2016.0044
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32703
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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