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Kidney Transplantation in Korean Patients With End-Stage Renal Disase Aged 65 and Older: A Single-Center Experience

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Author(s)
S.S. KangW.Y. ParkK. JinS.B. ParkS. Han
Keimyung Author(s)
Jin, Kyu BokPark, Sung BaePark, Woo YoungHan, Seung YeupKang, Seong Sik
Department
Kidney Institute (신장연구소)
Dept. of Internal Medicine (내과학)
Journal Title
Tansplantation Proceedings
Issued Date
2017
Volume
49
Issue
5
Abstract
Background. The mean age of patients starting dialysis in Korea has increased to older
than 60 years and the proportion of patients aged 65 and older exceeded 40% in 2014.
Although the number of elderly dialysis patients is increasing rapidly, percentages of
elderly patients undergoing kidney transplantation (KT) are very low.
Methods. We retrospectively reviewed the medical records of patients who underwent
KT at Keimyung University Dongsan Medical Center between 1982 and 2016. Elderly
patients ( 65 years old) were compared with the control group of patients in their early
sixties (60e64 years old).
Results. Among a total of 1209 KT patients, those in their early sixties totaled 34 (2.8%)
and the elderly totaled only 18 (1.5%). Patient and allograft survival rate showed no significant
differences between the elderly and those in their early sixties. Death with a
functioning graft accounted for 50% in both groups. However, occurrences of bacterial
infection and tuberculosis were higher in the elderly (P ¼ .011 and .047, respectively). In a
multivariate analysis, longer duration of renal replacement therapy before KT and the
occurrence of malignancy were independent risk factors for patient death (hazard ratio
[HR], 1.027; P ¼ .014; HR, 31.934; P ¼ .016, respectively). Also, albuminuria at 6 months
after KT was an independent risk factor for allograft loss (HR, 51.155; P ¼ .016).
Conclusion. The overall survival rate of the elderly was not significantly lower than those
in their early sixties. Even in the elderly, KT should not be delayed. In addition, careful
surveillance for malignancy and measures to decrease the risk of infection are necessary.
Keimyung Author(s)(Kor)
진규복
박성배
박우영
한승엽
강성식
Publisher
School of Medicine
Citation
S.S. Kang et al. (2017). Kidney Transplantation in Korean Patients With End-Stage Renal Disase Aged 65 and Older: A Single-Center Experience. Tansplantation Proceedings, 49(5), 987–991. doi: 10.1016/j.transproceed.2017.03.060
Type
Article
ISSN
0041-1345
Source
https://linkinghub.elsevier.com/retrieve/pii/S0041134517302804
DOI
10.1016/j.transproceed.2017.03.060
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32858
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
3. Research Institutues (연구소) > Kidney Institute (신장연구소)
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