계명대학교 의학도서관 Repository

Comparison of Resolute zotarolimus-eluting stents versus everolimus-eluting stents in patients with metabolic syndrome and acute myocardial infarction: Propensity score-matched analysis.

Metadata Downloads
Author(s)
Mi Seon JiMyung Ho JeongYoung Keun AhnSang Hyung KimYoung Jo KimShung Chull ChaeTaek Jong HongIn Whan SeongJei Keon ChaeChong Jin KimMyeong Chan ChoSeung-Woon RhaJang Ho BaeKi Bae SeungSeung Jung ParkSeung Ho Hur
Keimyung Author(s)
Hur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
International journal of cardiology
Issued Date
2015
Volume
199
Keyword
Metabolic cardiovascular syndromeMyocardial infarctionDrug-coated stents
Abstract
Background: Despite common use of second-generation drug-eluting stents in treating patientswith coronary artery
disease, there is lack of data comparing these stents exclusively in patients with acutemyocardial infarction
(AMI), especially with metabolic syndrome (MetS), which is highly prevalent in AMI and potential to worsen
clinical outcomes. The aim of this study was to compare clinical outcomes of everolimus-eluting stent (EES)
and Resolute-zotarolimus-eluting stent (R-ZES) in AMI patients with MetS, in terms of stent-related and
patient-related outcomes.
Methods: A total of 3942 AMI patients in the KAMIR (Korea Acute Myocardial Infarction Registry) were grouped
according to the presence ofMetS and stent type: EES (N=1582) and R-ZES (N=255) inMetS (1837). Target
lesion failure (TLF) and patient-oriented composite events (POCE) at 1 year were evaluated.
Results: InMetS patients, TLF (3.7% vs. 2.7%, p=0.592) and POCE (7.9% vs. 6.7%, p=0.764)were similar between
EES and R-ZES. Also in Non-MetS patients, TLF (3.9% vs. 3.1%, p=0.307) and POCE (6.4% vs. 7.3%, p=0.866)weresimilar between 2 groups. TLF was similar between MetS and Non-MetS patients (3.6% vs. 3.8%), while POCEs
(7.7% vs. 6.6%) were higher in MetS. Propensity-score matching analysis showed similar results between stent
groups in MetS and Non-MetS. In multivariate analysis, left ventricular ejection fraction and symptom-to-door
time were independent predictors of TLF and POCE in MetS patients with AMI.
Conclusions: In MetS patients with AMI, EES and R-ZES showed excellent performance and safety. However,
patient-oriented composite events were relatively high, suggesting more efforts to improve them.
Keimyung Author(s)(Kor)
허승호
Publisher
School of Medicine
Citation
Mi Seon Ji et al. (2015). Comparison of Resolute zotarolimus-eluting stents versus everolimus-eluting stents in patients with metabolic syndrome and acute myocardial infarction: Propensity score-matched analysis. International journal of cardiology, 199, 53–62. doi: 10.1016/j.ijcard.2015.07.010
Type
Article
ISSN
0167-5273
Source
https://www.sciencedirect.com/science/article/pii/S0167527315301340?via%3Dihub
DOI
10.1016/j.ijcard.2015.07.010
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32922
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.