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Gender Differences in the Clinical Characteristics of Psychotic Depression: Results from the CRESCEND Study

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Author(s)
Seon-Cheol ParkSøren Dinesen ØstergaardJae-Min KimTae-Youn JunMin-Soo LeeJung-Bum KimHyeon-Woo YimYong Chon Park
Keimyung Author(s)
Kim, Jung Bum
Department
Dept. of Psychiatry (정신건강의학)
Journal Title
Clinical Psychopharmacology and Neuroscience.
Issued Date
2015
Volume
13
Issue
3
Keyword
Psychotic depressionGenderSuicidal ideationHallucinatory behaviorIllness burden
Abstract
Objective: To test whether there are gender differences in the clinical characteristics of patients with psychotic depression (PD).
Methods: Using data from the Clinical Research Center for Depression (CRESCEND) study in South Korea, we tested for potential
gender differences in clinical characteristics among 53 patients with PD. The Psychotic Depression Assessment Scale (PDAS)
and other psychometric scales were used to evaluate various clinical features of the study subjects. Independent t-tests were
performed for normally distributed variables, Mann-Whitney U-tests for non-normally distributed variables, and χ2 tests for
discrete variables. In addition, to exclude the effects of confounding variables, we carried out an analysis of covariance (ANCOVA)
for the normally distributed variables and binary logistic regression analyses for discrete variables, after adjusting the effects
of marital status.
Results: We identified more prevalent suicidal ideation (adjusted odds ratio [aOR]=10.316, p=0.036) and hallucinatory behavior
(aOR=8.332, p=0.016), as well as more severe anxiety symptoms (degrees of freedom [df]=1, F=6.123, p=0.017), and poorer
social and occupational functioning (df=1, F=6.265, p=0.016) in the male patients compared to the female patients.
Conclusion: Our findings suggest that in South Korean patients with PD, suicidal ideation, hallucinatory behavior, and anxiety
is more pronounced among males than females. This should be taken into consideration in clinical practice.
Keimyung Author(s)(Kor)
김정범
Publisher
School of Medicine
Citation
Seon-Cheol Park et al. (2015). Gender Differences in the Clinical Characteristics of Psychotic Depression: Results from the CRESCEND Study. Clinical Psychopharmacology and Neuroscience., 13(3), 256–262. doi: 10.9758/cpn.2015.13.3.256
Type
Article
ISSN
1738-1088
DOI
10.9758/cpn.2015.13.3.256
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32970
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Psychiatry (정신건강의학)
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