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Hospital-Based Prospective Registration of Acute Transient Ischemic Attack and Noncerebrovascular Events in Korea

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Author(s)
Jun Young ChangDo Houng KimJin-Heon ChungKyu Sun YumJeong-Ho HongMoon-Ku Han
Keimyung Author(s)
Hong, Jeong Ho
Department
Dept. of Neurology (신경과학)
Journal Title
Journal of Stroke and Cerebrovascular Diseases.
Issued Date
2015
Volume
24
Issue
8
Keyword
TIATIA mimicsSteno-occlusive diseaseCardioembolic riskDiffusionweighted imaging
Abstract
Background: There have been no prospective studies on the clinical features, etiologies,
and outcome of transient ischemic attack (TIA) in Korea. The aim of this study
was to identify variables that can discriminate TIA from TIA mimics. Also we evaluated
the characteristic of TIA patients according to the presence of diffusionweighted
imaging (DWI) lesion. Methods: Patients were categorized into TIA and
TIA mimics according to the result of an initial workup. TIA patients were divided
according to the presence of DWI lesions. Baseline demographics, risk factors, laboratory
results, initial blood pressure, imaging findings, recurrence rate of TIA or
stroke at 3 months, and initial neurologic manifestations were prospectively
collected and compared. Results: We evaluated a total of 252 patients (212 with
TIA and 40 with TIA mimics). Steno-occlusion of the relevant artery (odds ratio
[OR], 22.39; 95% confidence interval [CI], 2.03-246.73) and cardioembolic risk (OR,
32.15; 95% CI, 1.12-922.97) were significantly associated with TIA. Amnesia (OR,
.001; 95% CI, .00-.05) and consciousness disturbance (OR, .003; 95% CI, .00-.06)
favored TIA mimics. Perfusion defect (OR, 5.56; 95% CI, 2.90-10.68) and cardioembolic
risk (OR, 2.68; 95% CI, 1.14-6.32) were significantly associated with DWI lesion.
Recurrence did not significantly differ according to the presence of a lesion on DWI
(positive, 4.9%; negative, 7.8%; P5.41). Conclusion: Steno-occlusive disease and cardioembolic
risk were independently associated with TIA. Perfusion defect and cardioembolic
risk predicted positive DWI lesion. The value of various imaging
modalities for predicting TIA etiology needs further evaluation.
Keimyung Author(s)(Kor)
홍정호
Publisher
School of Medicine
Citation
Jun Young Chang et al. (2015). Hospital-Based Prospective Registration of Acute Transient Ischemic Attack and Noncerebrovascular Events in Korea. Journal of Stroke and Cerebrovascular Diseases., 24(8), 1803–1810. doi: 10.1016/j.jstrokecerebrovasdis.2015.04.007
Type
Article
ISSN
1052-3057
Source
https://www.sciencedirect.com/science/article/pii/S1052305715001986?via%3Dihub
DOI
10.1016/j.jstrokecerebrovasdis.2015.04.007
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32975
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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