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The Effectiveness of Additional Treatment Modalities after the Failure of Recanalization by Thrombectomy Alone in Acute Vertebrobasilar Arterial Occlusion

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Author(s)
Seong Mook KimSung-Il Sohn,Jeong-Ho HongHyuk-Won ChangChang-Young LeeChang-Hyun Kim
Keimyung Author(s)
Sohn, Sung IlHong, Jeong HoChang, Hyuk WonLee, Chang YoungKim, Chang Hyun
Department
Dept. of Neurology (신경과학)
Dept. of Radiology (영상의학)
Dept. of Neurosurgery (신경외과학)
Journal Title
Journal of Korean Neurosurgical Society
Issued Date
2015
Volume
58
Issue
5
Keyword
Vertebrobasilar artery occlusionMechanical thrombectomyMultimodal treatment
Abstract
Objective : Acute vertebrobasilar artery occlusion (AVBAO) is a devastating disease with a high mortality rate. One of the most important factors affecting favorable clinical outcome is early recanalization. Mechanical thrombectomy is an emerging treatment strategy for achieving a high recanalization rates. However, thrombectomy alone can be insufficient to complete recanalization, especially for acute stroke involving large artery atheromatous disease. The purpose of this study is to investigate the safety and efficacy of mechanical thrombectomy in AVBAO.
Methods : Fourteen consecutive patients with AVBAO were treated with mechanical thrombectomy. Additional multimodal treatments were intra-arterial (IA) thrombolysis, balloon angioplasty, or permanent stent placement. Recanalization by thrombectomy alone and multimodal treatments were assessed by the Thrombolysis in Cerebral Infarction (TICI) score. Clinical outcome was determined using the National Institutes of Health Stroke Scale (NIHSS) at 7 days and the modified Rankin Scale (mRS) at 3 months.
Results : Thrombectomy alone and multimodal treatments were performed in 10 patients (71.4%) and 4 patients (28.6%), respectively. Successful recanalization (TICI 2b–3) was achieved in 11 (78.6%). Among these 11 patients, 3 (27.3%) underwent multimodal treatment due to underlying atherosclerotic stenosis. Ten (71.4%) of the 14 showed NIHSS score improvement of >10. Overall mortality was 3 (21.4%) of 14.
Conclusion : We suggest that mechanical thrombectomy is safe and effective for improving recanalization rates in AVBAO, with low complication rates. Also, in carefully selected patients after the failure of recanalization by thrombectomy alone, additional multimodal treatment such as IA thrombolysis, balloons, or stents can be needed to achieve successful recanalization.
Keimyung Author(s)(Kor)
손성일
홍정호
장혁원
이창영
김창현
Publisher
School of Medicine
Citation
Seong Mook Kim et al. (2015). The Effectiveness of Additional Treatment Modalities after the Failure of Recanalization by Thrombectomy Alone in Acute Vertebrobasilar Arterial Occlusion. Journal of Korean Neurosurgical Society, 58(5), 419–425. doi: 10.3340/jkns.2015.58.5.419
Type
Article
ISSN
2005-3711
DOI
10.3340/jkns.2015.58.5.419
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33058
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. School of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학)
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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