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The Severity and Pattern of Autonomic Dysfunction in Idiopathic Rapid Eye Movement Sleep Behavior Disorder

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Author(s)
Hyung LeeYong-Won ChoHyun Ah Kim
Keimyung Author(s)
Lee, HyungCho, Yong WonKim, Hyun Ah
Department
Dept. of Neurology (신경과학)
Brain Research Institute (뇌연구소)
Journal Title
Movement Disorders
Issued Date
2015
Volume
30
Issue
13
Keyword
REM sleep behavior disorderAutonomic nervous systemPrimary autonomic disorderSleep disorder
Abstract
Background: Autonomic dysfunction in idiopathic rapid
eye movement sleep behavior disorder patients has
not yet been quantified. The aim of this study was to
characterize dysautonomia in patients with idiopathic
rapid eye movement sleep behavior disorder using the
Composite Autonomic Severity Score, which is a validated
instrument for the quantitation of autonomic
failure.
Methods: We prospectively enrolled patients with idiopathic
rapid eye movement sleep behavior disorder. A
battery of standardized autonomic function tests was
performed. Autonomic data obtained from the patients
were compared to age- and sex-matched healthy
controls.
Results: Seventeen patients were enrolled. All but 1
patient showed at least one autonomic deficit. These
deficits were predominantly adrenergic and cardiovagal
and involved relatively few sudomotor problems. The
degree of autonomic dysfunction according to the
Composite Autonomic Severity Score was mild to
moderate in most patients.
Conclusions: Idiopathic rapid eye movement sleep
behavior disorder is linked to mild-to-moderate autonomic
dysfunction, which is predominantly adrenergic
and cardiovagal.
Keimyung Author(s)(Kor)
이형
조용원
김현아
Publisher
School of Medicine
Citation
Hyung Lee et al. (2015). The Severity and Pattern of Autonomic Dysfunction in Idiopathic Rapid Eye Movement Sleep Behavior Disorder. Movement Disorders, 30(13), 1843–1848. doi: 10.1002/mds.26416
Type
Article
ISSN
0885-3185
Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/mds.26416
DOI
10.1002/mds.26416
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33066
Appears in Collections:
3. Research Institutues (연구소) > Brain Research Institute (뇌연구소)
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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