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Brefeldin A-induced Endoplasmic Reticulum Stress Leads to Different CHOP Expression in Primary Astrocyte Cells and C6 Glioma Cells

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Author(s)
Eun Jung ParkTaeg Kyu Kwon
Keimyung Author(s)
Kwon, Taeg Kyu
Department
Dept. of Immunology (면역학)
Journal Title
Journal of Life Science
Issued Date
2016
Volume
26
Issue
4
Keyword
Astocyte cellsBrefeldin AC6 glioma cellsCHOPProteasome
Abstract
Premature infants requiring an ophthalmic examination or even surgery for retinopathy of prematurity (ROP) have a high prevalence of co-existing bronchopulmonary dysplasia (BPD). Reactive airway is one of the clinical presentations of BPD. We report two cases of bronchoconstriction following instillation of mydriatic eye drops. One occurred during induction of anesthesia for laser photocoagulation and the other before screening of ROP. The most likely cause in each case was phenylephrine eye drops. We recommend that the minimal dosage of phenylephrine needed to attain proper mydriasis should be instilled to infant patients, and the possibility of bronchoconstriction occurrence kept in mind, especially for infants with low body weight with BPD.
Keimyung Author(s)(Kor)
권택규
Publisher
School of Medicine
Citation
Eun Jung Park and Taeg Kyu Kwon. (2016). Brefeldin A-induced Endoplasmic Reticulum Stress Leads to Different CHOP
Expression in Primary Astrocyte Cells and C6 Glioma Cells. Journal of Life Science, 26(4), 490–495. doi: 10.5352/JLS.2016.26.4.490
Type
Article
ISSN
1225-9918
DOI
10.5352/JLS.2016.26.4.490
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33144
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Immunology (면역학)
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