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Clinical Findings According to Feeding Diets in Very Low Birth Weight Infants: Human Breast Milk versus Bovine Milk-Based Formula

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Author(s)
Sang Hyun LeeJae Hyun ParkChun Soo KimSang Lak Lee
Keimyung Author(s)
Park, Jae HyunKim, Chun SooLee, Sang Lak
Department
Dept. of Pediatrics (소아청소년학)
Journal Title
Neonatal Medicine
Issued Date
2016
Volume
23
Issue
1
Keyword
Human breast milkInfantVery low birth weight
Abstract
Purpose: We aimed to compare the clinical findings, including morbidity, duration of parenteral nutrition, and length of hospital stay between very low birth weight infants (VLBWIs) fed bovine milk-based formula (BOV) and VLBWIs fed human breast milk (HBM) in a neonatal intensive care unit (NICU).
Methods: VLBWIs admitted to the NICU of Dongsan Medical Center, Keimyung University, were enrolled. Infants born from March to August 2014 (n=28) were fed BOV (the BOV group), and those born from September to December 2014 (n=18) were fed HBM (the HBM group). Pasteurized (heating at 62.5˚C for 30 minutes) donor human milk was used if the mother’s own milk was not available because of insufficient breast milk production.
Results: The gestational age (28.0±1.7 weeks vs. 27.8±1.4 weeks) and birth weight (1,055±265 g vs. 1,175±187 g), of the infants in the BOV and HBM, groups were similar. In addition, perinatal characteristics were similar between the groups. The duration of parenteral nutrition (36.4 days vs. 24.1 days, P=0.038), length of hospital stay (74.3 days vs.61.1 days, P=0.037), and incidence of nosocomial sepsis (53.6% vs. 22.2%, P= 0.035), significantly differed between the BOV and HBM groups. Furthermore, the frequency of feeding intolerance was higher in the BOV group than in the HBM group, but this difference was not significant. Perinatal cytomegalovirus infection was not detected in any of the infants fed pasteurized donor human milk.
Conclusion: Human-breast-milk-based diet for VLBWIs significantly reduces the incidence of nosocomial sepsis, duration of parenteral nutrition, and length of hospital stay.
Keimyung Author(s)(Kor)
박재현
김천수
이상락
Publisher
School of Medicine
Citation
Sang Hyun Lee et al. (2016). Clinical Findings According to Feeding Diets in Very Low Birth Weight Infants: Human Breast Milk versus Bovine Milk-Based Formula. Neonatal Medicine, 23(1), 23–28. doi: 10.5385/nm.2016.23.1.23
Type
Article
ISSN
2287-9803
DOI
10.5385/nm.2016.23.1.23
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33153
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
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