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Complications Requiring Hospital Admission and Causes of In-Hospital Death over Time in Alcoholic and Nonalcoholic Cirrhosis Patients.

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Author(s)
Hee Yeon KimChang Wook KimJong Young ChoiChang Don LeeSae Hwan LeeMoon Young KimByoung Kuk JangHyun Young Woo
Keimyung Author(s)
Jang, Byoung Kuk
Department
Dept. of Internal Medicine (내과학)
Journal Title
Gut and liver
Issued Date
2016
Volume
10
Issue
1
Keyword
Cause of deathComplicationsHospitalizationLiver cirrhosis
Abstract
Background/Aims: Data on the epidemiology of alcoholic cirrhosis, especially in Asian countries, are limited. We compared the temporal evolution of patterns of alcoholic and nonalcoholic cirrhosis over the last decade. Methods: We retrospectively examined the inpatient datasets of five referral centers during 2002 and 2011. The study included patients who were admitted due to specific complications of liver cirrhosis. We compared the causes of hospital admissions and in-hospital deaths between patients with alcoholic and nonalcoholic cirrhosis. Results: Among the included 2,799 hospitalizations (2,165 patients), 1,496 (1,143 patients) were from 2002, and 1,303 (1,022 patients) were from 2011. Over time, there was a reduction in the rate of hepatic encephalopathy (HE) as a cause of hospitalization and an increase in the rate of hepatocellular carcinoma. Deaths that were attributable to HE or spontaneous bacterial peritonitis (SBP) significantly decreased, whereas those due to hepatorenal syndrome (HRS) significantly increased over time in patients with alcoholic cirrhosis. However, in patients with nonalcoholic cirrhosis, hepatic failure and HRS remained the principal causes of in-hospital death during both time periods. Conclusions: The major causes of in-hospital deaths have evolved from acute cirrhotic complications, including HE or SBP to HRS in alcoholic cirrhosis, whereas those have remained unchanged in nonalcoholic cirrhosis during the last decade.
Keimyung Author(s)(Kor)
장병국
Publisher
School of Medicine
Citation
Hee Yeon Kim et al. (2016). Complications Requiring Hospital Admission and Causes of In-Hospital Death over Time in Alcoholic and Nonalcoholic Cirrhosis Patients. Gut and liver, 10(1), 95–100. doi: 10.5009/gnl14363
Type
Article
ISSN
1976-2283
DOI
10.5009/gnl14363
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33170
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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