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Health-Related Quality of Life of Kidney Transplantation Patients: Results from the KoreaN Cohort Study for Outcome in Patients With Kidney Transplantation (KNOW-KT) Study

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Author(s)
H.J. LimT.Y. KooJ. LeeK.H. HuhJ.B. ParkJ. ChoS. LeeH. RoS. HanB. ParkS. ParkW. ChungS.K. ParkC. KimS.J. KimY.S. KimC. AhnJ. Yangthe KNOW-KT Study Group
Keimyung Author(s)
Han, Seung YeupPark, Sung Bae
Department
Dept. of Internal Medicine (내과학)
Journal Title
Transplantation Proceedings.
Issued Date
2016
Volume
48
Issue
3
Abstract
Background. As patient and graft survival rates have been improving after kidney
transplantation, health-related quality of life (HR-QOL) has become an important
indicator of effective treatment. This study aimed to evaluate changes in HR-QOL after
kidney transplantation.
Materials and Methods. The KoreaN cohort study for Outcome in patients With Kidney
Transplantation (KNOW-KT) is a multicenter, observational, 9-year, cohort study. The
HR-QOL of patients in the KNOW-KT study was assessed before transplantation and 2
years after transplantation using the Kidney Disease Quality of Life Short Form
(KDQOL-SF) including chronic kidney disease targeted area and the Medical Outcome
Study 36-item Short Form Health Survey (SF-36). Multivariate linear regression was
used to identify significant factors associated with follow-up QOL scores.
Results. A total of 175 patients from 8 centers were analyzed. All QOL scores including
the total QOL score, chronic kidney disease targeted score, and SF-36 at the 2-year followup
were significantly increased compared to baseline values. Both physical and mental scale
scores were improved after transplantation.
Conclusion. The QOL scores for both the mental and physical scales were improved at 2
years after kidney transplantation. High glomerular filtration rate at 2 years, high baseline
QOL score, and low body mass index were associated with good follow-up QOL scores.
Kidney transplantation for an Asian population with end-stage renal disease can result
in better QOL as well as better patient and graft survival.
Keimyung Author(s)(Kor)
한승엽
박성배
Publisher
School of Medicine
Citation
H.J. Lim et al. (2016). Health-Related Quality of Life of Kidney Transplantation Patients: Results from the KoreaN Cohort Study for Outcome in Patients With Kidney Transplantation (KNOW-KT) Study. Transplantation Proceedings., 48(3), 844–847. doi: 10.1016/j.transproceed.2015.12.101
Type
Article
ISSN
0041-1345
Source
https://www.sciencedirect.com/science/article/pii/S0041134516002207?via%3Dihub
DOI
10.1016/j.transproceed.2015.12.101
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33214
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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