계명대학교 의학도서관 Repository

Living near nuclear power plants and thyroid cancer risk: A systematic review and meta-analysis

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Author(s)
Jaeyoung KimYejin BangWon Jin Lee
Keimyung Author(s)
Kim, Jae Young
Department
Dept. of Preventive Medicine (예방의학)
Journal Title
Environment International
Issued Date
2016
Volume
87
Keyword
Thyroid glandNeoplasmRadiationEnvironmental exposure
Abstract
There has been public concern regarding the safety of residing near nuclear power plants, and the extent of risk
for thyroid cancer among adults living near nuclear power plants has not been fully explored. In the present
study, a systematic review and meta-analysis of epidemiologic studies was conducted to investigate the association
between living near nuclear power plants and the risk of thyroid cancer. A comprehensive literature search
was performed on studies published up to March 2015 on the association between nuclear power plants and thyroid
cancer risk. The summary standardized incidence ratio (SIR), standardized mortality ratio (SMR), and 95%
confidence intervals (CIs) were calculated using a random-effect model of meta-analysis. Sensitivity analyses
were performed by study quality. Thirteen studies were included in the meta-analysis, covering 36 nuclear
power stations in 10 countries. Overall, summary estimates showed no significant increased thyroid cancer incidence
or mortality among residents living near nuclear power plants (summary SIR = 0.98; 95% CI 0.87–1.11,
summary SMR=0.80; 95% CI 0.62–1.04). The pooled estimates did not reveal different patterns of risk by gender,
exposure definition, or reference population. However, sensitivity analysis by exposure definition showed that
living less than 20 km from nuclear power plants was associated with a significant increase in the risk of thyroid
cancer in well-designed studies (summary OR=1.75; 95% CI 1.17–2.64). Our study does not support an association
between living near nuclear power plants and risk of thyroid cancer but does support a need for welldesigned
future studies.
Keimyung Author(s)(Kor)
김재영
Publisher
School of Medicine
Citation
Jaeyoung Kim et al. (2016). Living near nuclear power plants and thyroid cancer risk: A systematic review and meta-analysis. Environment International, 87, 42–48. doi: 10.1016/j.envint.2015.11.006
Type
Article
ISSN
0160-4120
Source
https://www.sciencedirect.com/science/article/pii/S0160412015300908?via%3Dihub
DOI
10.1016/j.envint.2015.11.006
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33230
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학)
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