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Looking at the self in front of others: Neural correlates of attentional bias in social anxiety

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Author(s)
Soo-Hee ChoiJung-Eun ShinJeonghun KuJae-Jin Kim
Keimyung Author(s)
Ku, Jeong Hun
Department
Dept. of Biomedical Engineering (의용공학과)
Journal Title
Journal of Psychiatric Research
Issued Date
2016
Volume
75
Keyword
Attentional biasSocial anxiety disorderLateral orbitofrontal cortexPosterior cingulate cortex
Abstract
In social anxiety disorder (SAD), anxiety reactions are triggered by attentional bias to social threats that
automatically appear in social situations. The present study aimed to investigate the neural basis and
underlying resting-state pathology of attentional bias toward internal and external social threats as a
core element of SAD. Twenty-two patients with SAD and 20 control subjects scanned functional magnetic
resonance imaging during resting-state and while performing the visual search task. During the
task, participants were exposed to internal threat (hearing participants’ own pulse-sounds) and external
threat (crowds in facial matrices). Patients showed activations in the lateral orbitofrontal cortex, rostral
anterior cingulate cortex and insula in response to internal threat and activations in the posterior
cingulate cortex and middle temporal gyrus in response to external threat. In patients, neural activity
related to combined internal and external threats in the posterior cingulate cortex was inversely
correlated with the functional connectivity strengths with the default mode network during restingstate.
These findings suggest that attentional bias may stem from limbic and paralimbic pathology,
and the interactive process of internally- and externally-focused attentional bias in SAD is associated
with the self-referential function of resting-state.
Keimyung Author(s)(Kor)
구정훈
Publisher
School of Medicine
Citation
Soo-Hee Choi et al. (2016). Looking at the self in front of others: Neural correlates of attentional bias in social anxiety. Journal of Psychiatric Research, 75, 31–40. doi: 10.1016/j.jpsychires.2016.01.001
Type
Article
ISSN
0022-3956
Source
https://www.sciencedirect.com/science/article/pii/S0022395616300012?via%3Dihub
DOI
10.1016/j.jpsychires.2016.01.001
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33233
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Biomedical Engineering (의용공학과)
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