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Multiple daily injection of insulin regimen for a 10-month-old infant with type 1 diabetes mellitus and diabetic ketoacidosis

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Author(s)
Ji Hyun ParkSo Young ShinYe Jee ShimJin Hyeok ChoiHeung Sik Kim
Keimyung Author(s)
Shim, Ye JeeChoi, Jin HyeokKim, Heung Sik
Department
Dept. of Pediatrics (소아청소년학)
Journal Title
Annals of Pediatric Endocrinology & Metabolism
Issued Date
2016
Volume
21
Issue
2
Keyword
Diabetic ketoacidosisInfantType 1 diabetes mellitus
Abstract
The incidence of type 1 diabetes is increasing worldwide, and the greatest increase has been observed in very young children under 4 years of age. A case of infantile diabetic ketoacidosis in a 10-month-old male infant was encountered by these authors. The infant's fasting glucose level was 490 mg/dL, his PH was 7.13, his pCO2 was 15 mmHg, and his bicarbonate level was 5.0 mmol/L. The glycosylated hemoglobin level had increased to 9.4%. Ketonuria and glucosuria were detected in the urinalysis. The fasting C-peptide and insulin levels had decreased. The infant was positive for anti-insulin and antiglutamic acid decarboxylase antibodies. Immediately after the infant's admission, fluid therapy and intravenous insulin infusion therapy were started. On the second day of the infant's hospitalization and after fluid therapy, he recovered from his lethargic condition, and his general condition improved. Feeding was started on the third day, and he was fed a formula 5 to 7 times a day and ate rice, vegetables, and lean meat. Due to the frequent feeding, the frequency of rapid-acting insulin injection was increased from 3 times before feeding to 5 times, adjusted according to the feeding frequency. The total dose of insulin that was injected was 0.8-1.1 IU/kg/day, and the infant was discharged on the 12th day of his hospitalization. The case is presented herein with a brief review of the relevant literature.
Keimyung Author(s)(Kor)
심예지
최진혁
김흥식
Publisher
School of Medicine
Citation
Ji Hyun Park et al. (2016). Multiple daily injection of insulin regimen for a 10-month-old infant with type 1 diabetes mellitus and diabetic ketoacidosis. Annals of Pediatric Endocrinology & Metabolism, 21(2), 96–98. doi: 10.6065/apem.2016.21.2.96
Type
Article
ISSN
2287-1012
DOI
10.6065/apem.2016.21.2.96
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33241
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
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