계명대학교 의학도서관 Repository

Pulmonary Outcomes of Early Extubation in Extremely Premature Infants (Gestational Age: 25–26 Weeks) with Synchronized Nasal Intermittent Positive-Pressure Ventilation

Metadata Downloads
Author(s)
Eun Mi ChoiJae Hyun ParkChun Soo KimSang Lak Lee
Keimyung Author(s)
Park, Jae HyunKim, Chun SooLee, Sang Lak
Department
Dept. of Pediatrics (소아청소년학)
Journal Title
Neonatal Medicine
Issued Date
2016
Volume
23
Issue
2
Keyword
Extremely premature infantsNoninvasive ventilation
Abstract
Purpose:

To investigate the pulmonary outcomes of early extubation (within the first 24 hours of life) with synchronized nasal intermittent positive pressure ventilation (NIPPV) in extremely premature infants born at 25–26 weeks' gestation.


Methods:

Medical records of extremely premature infants (gestational age: 25–26 weeks) born and admitted to the Keimyung University Dongsan Medical Center between January 2015 and December 2015 (n=42) were reviewed retrospectively. The early extubation group included infants who were extubated within the first 24 hours of life and was compared with a control group that included infants who remained ventilated beyond the first 24 hours of life. Extubation failure was defined as the need for reintubation within 72 hours after extubation.


Results:

Of the 35 enrolled infants, 22 (62.9%) were extubated within the first 24 hours of life. No significant differences in perinatal factors were observed between the early extubation and control groups. Between the two groups, the incidence rates of extubation failure (18.2% [4/22] vs. 7.7% [1/13], P=0.39), reintubation (50.0% [11/ 22] vs. 46.2% [6/13], P=0.84), mortality (18.2% [4/22] vs. 15.4% [2/13], P=0.83), and the combined rates of clinical bronchopulmonary dysplasia (BPD) or death (40.9% [9/22] vs. 38.5% [5/13], P=0.89) did not significantly differ.


Conclusion:

Early extubation (within the first 24 hours of life) with synchronized NIPPV is safe and effective in the extremely premature infants born at 25-26 weeks' gestation, and does not indicate increased risks of extubation failure and other morbidities.
Keimyung Author(s)(Kor)
박재현
김천수
이상락
Publisher
School of Medicine
Citation
Eun Mi Choi et al. (2016). Pulmonary Outcomes of Early Extubation in Extremely Premature Infants (Gestational Age: 25–26 Weeks) with Synchronized Nasal Intermittent Positive-Pressure Ventilation. Neonatal Medicine, 23(2), 81–87. doi: 10.5385/nm.2016.23.2.81
Type
Article
ISSN
2287-9412
DOI
10.5385/nm.2016.23.2.81
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33271
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
Authorize & License
  • Authorize공개
Files in This Item:

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.