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Risk Factors Associated with Rebleeding in Patients with High Risk Peptic Ulcer Bleeding: Focusing on the Role of Second Look Endoscopy

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Author(s)
Sung Bum KimSi Hyung LeeKyeong Ok KimByung Ik JangTae Nyeun KimSeong Woo JeonJoong Goo KwonEun Young KimJin Tae JungKyung Sik ParkKwang Bum ChoEun Soo KimHyun Jin KimChang Keun ParkJeong Bae ParkChang Heon Yang
Keimyung Author(s)
Park, Kyung SikCho, Kwang BumKim, Eun Soo
Department
Dept. of Internal Medicine (내과학)
Journal Title
Digestive Diseases and Sciences
Issued Date
2016
Volume
61
Issue
2
Keyword
RebleedingStomach ulcerDuodenal ulcerSecond look endoscopyBlood transfusion
Abstract
Background Re-bleeding after initial hemostasis in peptic
ulcer bleeding can be life threatening. Identification of
factors associated with re-bleeding is important. The aims
of this study were to determine incidence of rebleeding in
patients with high risk peptic ulcer bleeding and to evaluate
factors associated with rebleeding.
Methods Among patients diagnosed as upper gastrointestinal
hemorrhage at seven hospitals in Daegu–Gyeongbuk,
and one hospital in Gyeongnam, South Korea, from
Feb 2011 to Dec 2013, 699 patients diagnosed as high risk
peptic ulcer bleeding with Forrest classification above llb
were included. The data were obtained in a prospective
manner.
Results Among 699 patients, re-bleeding occurred in 64
(9.2 %) patients. Second look endoscopy was significantly
more performed in the non-rebleeding group than the
rebleeding group (81.8 vs 62.5 %, p\0.001). In multivariate
analysis, use of non-steroidal anti-inflammatory
agents, larger transfusion volume (C5 units), and nonperformance
of second look endoscopy were found as risk
factors for rebleeding in high risk peptic ulcer bleeding.
Conclusion In our study, rebleeding was observed in
9.2 % of patients with high risk peptic ulcer bleeding.
Performance of second look endoscopy seems to lower the
risk of rebleeding in high risk peptic ulcer bleeding patients
and caution should be paid to patients receiving high volume
transfusion and on medication with NSAIDs.
Keimyung Author(s)(Kor)
박경식
조광범
김은수
Publisher
School of Medicine
Citation
Sung Bum Kim et al. (2016). Risk Factors Associated with Rebleeding in Patients with High Risk Peptic Ulcer Bleeding: Focusing on the Role of Second Look Endoscopy. Digestive Diseases and Sciences, 61(2), 517–522. doi: 10.1007/s10620-015-3846-y
Type
Article
ISSN
0163-2116
Source
https://link.springer.com/article/10.1007%2Fs10620-015-3846-y
DOI
10.1007/s10620-015-3846-y
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33283
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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