계명대학교 의학도서관 Repository

Prevalence and Seroprevalence of High-Risk Human Papillomavirus Infection

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Author(s)
Min-A KimJin-Kyoung OhDoo Byung ChayDong Choon ParkSeok Mo KimEun-Suk KangJae-Hoon KimChi-Heum ChoHai-Rim ShinKyung Seo
Keimyung Author(s)
Cho, Chi Heum
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
Obstetrics & Gynecology
Issued Date
2010
Volume
116
Issue
4
Abstract
OBJECTIVE: To estimate the prevalence and seroprevalence
of high-risk human papillomavirus (HPV) in Korean
girls and women.
METHODS: We estimated the seroprevalence of HPV
subtypes 16 and 18 among 1,094 girls and women aged
9–59 years and the prevalence of genital high-risk HPV
among 902 women aged 20–59 years who visited our
institution for a medical checkup. Genital high-risk HPV
DNA was measured using liquid hybridization and polymerase
chain reaction assays. Serum antibodies to HPV
subtypes 16 and 18 were measured using a multiplexed
competitive luminex technique.
RESULTS: The prevalence of genital high-risk HPV was
12.6% among Korean women aged 20–59 years. It reached
a peak of 23.2% at 20–29 years of age, decreasing thereafter
but increasing again to 12.4% at 50–59 years of age. Human
papillomavirus 56 was the most common subtype followed
by HPV 18, HPV 52, and HPV 16. The seroprevalence of HPV
subtypes 16 and 18 was 8.7% among Korean girls and
women aged 9–59 years. It reached its highest peak of
13.4% at 25–29 years of age and decreased thereafter. It
then reached a second peak of 10.9% at 40–49 years of age
and plateaued thereafter. The seroprevalences of HPV subtypes
16 and 18 were 7.4% and 2.7%, respectively. In
multivariable analysis, the prevalence and seroprevalence
of high-risk HPV were correlated only with the number of
lifetime sexual partners.
CONCLUSION: High-risk HPV infection is common
among Korean women. Our epidemiological data on
high-risk HPV infection will help to assess vaccine policy
and to establish a baseline for estimating vaccine efficacy.
(Obstet Gynecol 2010;116:932–40)
Keimyung Author(s)(Kor)
조치흠
Publisher
School of Medicine
Citation
Min-A Kim et al. (2010). Prevalence and Seroprevalence of High-Risk Human Papillomavirus Infection. Obstetrics & Gynecology, 116(4), 932–940. doi: 10.1097/AOG.0b013e3181edbeba
Type
Article
ISSN
0029-7844
Source
https://insights.ovid.com/pubmed?pmid=20859158
DOI
10.1097/AOG.0b013e3181edbeba
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33584
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
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