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The Clinical Research Center for Depression Study: Baseline Characteristics of a Korean Long-Term Hospital-Based Observational Collaborative Prospective Cohort Study

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Author(s)
Tae-Suk KimSeung Hee JeongJung-Bum KimMin-Soo LeeJae-Min KimHyeon-Woo YimTae-Youn Jun
Keimyung Author(s)
Kim, Jung Bum
Department
Dept. of Psychiatry (정신건강의학)
Journal Title
Psychiatry investigation
Issued Date
2011
Volume
8
Issue
1
Keyword
DepressionHospital-basedLongitudinalObservationalProspective
Abstract
Objective

The Clinical Research Center for Depression (CRESCEND) study is a 9-year observational collaborative prospective cohort study for the clinical outcomes in participants with depressive disorders in Korea. In this study, we examined the baseline characteristics of the depressive participants as the hospital-based cohort.


Methods

Participants were assessed using various instruments including the Clinical Global Impression scale, 17-item Hamilton Depression Rating Scale (HDRS-17), Hamilton Anxiety Rating Scale, Brief Psychiatric Rating Scale, Social and Occupational Functioning Assessment Scale, Beck Depression Inventory-Second Edition, Scale for Suicide Ideation, and World Health Organization Quality of Life assessment instruments-abbreviated version. Also, personal histories of medical and psychiatric illnesses and the range of socio-epidemiologic and clinical data were collected from each participant.


Results

One thousand one hundred eighty three participants were recruited from 18 hospitals. The mean age of the participants was 47.9±15.9 year-old, 74.4% were female, 82.9% had been diagnosed of major depressive disorder, 40.9% were experiencing their first depressive episode, and 21.4% had a past history of suicide attempts. The majority (85.3%) of the participants were moderately to severely ill. The average HDRS-17 was 19.8±6.1. Significant gender differences at baseline were shown in age, education, marriage, employment, religion, and first depressive episode.


Conclusion

The baseline findings in the CRESCEND study showed some different characteristics of depression in Korea, suggesting a possibility of ethnic and cultural factors in depression.

Keywords: Depression, Hospital-based, Longitudinal, Observational, Prospective
Keimyung Author(s)(Kor)
김정범
Publisher
School of Medicine
Citation
Tae-Suk Kim et al. (2011). The Clinical Research Center for Depression Study: Baseline Characteristics of a Korean Long-Term Hospital-Based Observational Collaborative Prospective Cohort Study. Psychiatry investigation, 8(1), 1–8. doi: 10.4306/pi.2011.8.1.1
Type
Article
ISSN
1738-3684
DOI
10.4306/pi.2011.8.1.1
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33709
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Psychiatry (정신건강의학)
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