계명대학교 의학도서관 Repository

The Symptom Frequency Characteristics of the Hamilton Depression Rating Scale and Possible Symptom Clusters of Depressive Disorders in Korea: The CRESCEND Study

Metadata Downloads
Author(s)
Sae-Heon JangYoung-Nam ParkYoung-Myo JaeTae-Youn JunMin-Soo LeeJae-Min KimSeung-Hee JeongJung-Bum Kim
Keimyung Author(s)
Kim, Jung Bum
Department
Dept. of Psychiatry (정신건강의학)
Journal Title
Psychiatry Investigation
Issued Date
2011
Volume
8
Issue
4
Keyword
Symptom frequencyVariationHDRS-17Core symptoms clusterAssociate symptoms clusterSituation-specific symptoms cluster
Abstract
Objective

This study analyzed the symptom frequencies of 17-item Hamilton Depression Rating Scale (HDRS-17) to understand the characteristics of each item and to propose the possible symptoms clusters.


Methods

From psychiatric clinics of 18 Hospitals in Korea, 1,183 patients, diagnosed with major depressive disorder (psychotic or non-psychotic), dysthymia or depressive disorder not otherwise specified. according to DSM-IV criteria, participated in this study from January 2006 to August 2008. The frequencies of each item of HDRS-17 were analyzed according to sex and severity. In addition, we compared this study with a previous study performed in England by Hamilton and with two studies performed in Korea by Kim et al.


Results

The frequencies of HDRS-17 items varied widely in this study, ranging from 95.8% in work and activities to 37.4% in loss of weight. But, depressed mood, psychic anxiety and work and activities items exhibited constant and higher frequency or rank regardless of study, the severity of depression or sex. Insomnia early, somatic gastrointestinal, genital symptoms and insight showed relatively constant but lower frequency or rank in disregard of studies or the clinical variables. Other symptoms had variable frequencies or ranks according to the variable clinical situations (culture, time, sex, severity of depression).


Conclusion

We propose three clusters of symptoms in depressive disorders: core symptoms cluster, an associated symptoms, and a situation-specific symptoms. We can use these possible symptom clusters of depression in simplifying diagnosis of depression, increasing diagnostic specificity in special situation and indexing disease severity.

Keywords: Symptom frequency, Variation, HDRS-17, Core symptoms cluster, Associate symptoms cluster, Situation-specific symptoms cluster
Keimyung Author(s)(Kor)
김정범
Publisher
School of Medicine
Citation
Sae-Heon Jang et al. (2011). The Symptom Frequency Characteristics of the Hamilton Depression Rating Scale and Possible Symptom Clusters of Depressive Disorders in Korea: The CRESCEND Study. Psychiatry Investigation, 8(4), 312–319. doi: 10.4306/pi.2011.8.4.312
Type
Article
ISSN
1738-3684
DOI
10.4306/pi.2011.8.4.312
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33715
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Psychiatry (정신건강의학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.