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The Clinical Characteristics of Colonic Pseudo-obstruction and the Factors Associated with Medical Treatment Response: A Study Based on a Multicenter Database in Korea

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Author(s)
Kwang Jae LeeKee Wook JungSeung-Jae MyungHyun Jin KimNa Young KimYoung Hoon YoonChong Il SohnJung Eun ShinYu Kyung ChoSoo Jin HongTae Hee LeeKyung Sik ParkHye-Kyung JungChang Hwan ChoiGwang Ha KimJae Hak KimYoon Ju JoJoon Seong LeeHyo-Jin Park
Keimyung Author(s)
Park, Kyung Sik
Department
Dept. of Internal Medicine (내과학)
Journal Title
Journal of Korean Medical Science
Issued Date
2014
Volume
29
Issue
5
Keyword
Colonic Pseudo-obstructionAbdominal DistensionColonic DilatationTransition Zone
Abstract
Colonic pseudo-obstruction (CPO) is defined as marked colonic distension in the absence of
mechanical obstruction. We aimed to investigate the clinical characteristics of CPO and the
factors associated with the response to medical treatment by using a multicenter database
in Korea. CPO was diagnosed as colonic dilatation without mechanical obstruction by using
radiologic and/or endoscopic examinations. Acute CPO occurring in the postoperative
period in surgical patients or as a response to an acute illness was excluded. CPO cases
were identified in 15 tertiary referral hospitals between 2000 and 2011. The patients’ data
were retrospectively reviewed and analyzed. In total, 104 patients (53 men; mean age at
diagnosis, 47 yr) were identified. Seventy-seven of 104 patients (74%) showed a transition
zone on abdominal computed tomography. Sixty of 104 patients (58%) showed poor
responses to medical treatment and underwent surgery at the mean follow-up of 7.4
months (0.5-61 months). Younger age at the time of diagnosis, abdominal distension as a
chief complaint, and greater cecal diameter were independently associated with the poor
responses to medical treatment. These may be risk factors for a poor response to medical
treatment.
Keimyung Author(s)(Kor)
박경식
Publisher
School of Medicine
Citation
Kwang Jae Lee et al. (2014). The Clinical Characteristics of Colonic Pseudo-obstruction and the Factors Associated with Medical Treatment Response: A Study Based on a Multicenter Database in Korea. Journal of Korean Medical Science, 29(5), 699–703. doi: 10.3346/jkms.2014.29.5.699
Type
Article
ISSN
1011-8934
DOI
10.3346/jkms.2014.29.5.699
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33811
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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