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Primary stent therapy for symptomatic intracranial atherosclerotic stenosis: 1-year follow-up angiographic and midterm clinical outcomes

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Author(s)
CHANG-YOUNG LEEMAN-BIN YIM
Keimyung Author(s)
Lee, Chang YoungYim, Man Bin
Department
Dept. of Neurosurgery (신경외과학)
Brain Research Institute (뇌연구소)
Journal Title
Journal of Neurosurgery
Issued Date
2006
Volume
105
Issue
2
Keyword
intracranial lesionatherosclerosisintracranial stenosisstent
Abstract
Object. The aim of this study was to report 1-year angiographic follow-up results and midterm clinical outcomes in
patients with symptomatic intracranial atherosclerotic lesions treated with stent placement.
Methods. Ten patients with ischemic symptoms referable to stenotic intracranial atherosclerotic arteries, with greater
than 60% stenosis, underwent elective surgery in which a primary stent was placed. All patients underwent pretreatment
($ 1 week) combination oral antiplatelet (clopidogrel and aspirin) therapy and long-term (6-month) combination
oral antiplatelet (clopidogrel and aspirin) therapy after stents were placed. The procedure involved selecting stents of
the same size as the diameter of the target vessel and slowly inflating the balloon to its nominal pressure. One-year angiography
and midterm clinical follow-up data were obtained.
The stents were successfully placed in all patients without any perioperative complication. The mean preoperative
stenosis rate of 81% decreased to 4% after the stent was placed. Nine patients who underwent follow-up angiography
(one patient refused) at a mean of 12.3 months (range 10–19 months) had no changes in luminal diameter compared
with the immediate postoperative luminal diameter. Luminal narrowing increased, from 15 to 38%, in one case in
which there was comparatively greater residual stenosis (15%). No patient suffered new ischemic symptoms during a
mean clinical follow-up period of 21 months (range 12–36 months).
Conclusions. Elective stent surgery can provide good angiographic and clinical midterm outcomes in patients with
symptomatic intracranial atherosclerotic stenosis, and the procedure is associated with a high degree of technical success.
Reassessment of these promising results is needed in a larger population and in a randomized prospective comparison
study.
Keimyung Author(s)(Kor)
이창영
임만빈
Publisher
School of Medicine
Citation
CHANG-YOUNG LEE and MAN-BIN YIM. (2006). Primary stent therapy for symptomatic intracranial atherosclerotic stenosis: 1-year follow-up angiographic and midterm clinical outcomes. Journal of Neurosurgery, 105(2), 235–241.
Type
Article
ISSN
0022-3085
Source
http://thejns.org/doi/abs/10.3171/jns.2006.105.2.235?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33830
Appears in Collections:
3. Research Institutues (연구소) > Brain Research Institute (뇌연구소)
1. School of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학)
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