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Is the Psychotic Depression Assessment Scale a useful diagnostic tool?: The CRESCEND study

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Author(s)
Seon-Cheol ParkJoonho ChoiJae-Min KimTae-Youn JunMin-Soo LeeJung-Bum KimHyeon-Woo YimYong Chon Park
Keimyung Author(s)
Kim, Jung Bum
Department
Dept. of Psychiatry (정신건강의학)
Journal Title
Journal of Affective Disorders
Issued Date
2014
Volume
166
Keyword
Psychotic Depression Assessment Scale (PDAS)Psychotic depression (PD)Hallucinatory behaviorEmotional withdrawalDifferential diagnosis
Abstract
Background.

The Psychotic Depression Assessment Scale (PDAS) has been validated as a method of assessing the severity and treatment outcomes of psychotic depression (PD). We aimed to compare the results of the PDAS in PD and non-psychotic depression (non-PD) patients and validate the PDAS as a diagnostic tool for PD.


Methods.

We included 53 patients with PD and 441 with non-PD who participated in the Clinical Research Center for Depression study in South Korea. In addition to the PDAS, psychometric tools including the HAMD17, HAMA, BPRS, CGI-S, SOFAS, SSI-Beck, WHOQOL-BREF, AUDIT, and FTND were used to assess, respectively, depression, anxiety, overall symptoms, global severity, social functioning, suicidal ideation, quality of life, alcohol use, and nicotine use.


Results.

After adjusting for age and total HAMD17 score, PD patients had higher scores for depressive mood, hallucinations, unusual thought content, suspiciousness, blunted affect, and emotional withdrawal on the PDAS and higher total scores on the SSI-Beck than non-PD patients. Binary logistic regression identified hallucinatory behavior and emotional withdrawal as predictors of PD. Receiver operating characteristic analysis showed that emotional withdrawal could be used to differentiate psychotic from non-psychotic depression.


Limitations
.
The inter-rater reliability for psychometric assessments was not evaluated.


Conclusions.

In addition to assessing the severity and treatment outcomes of PD, PDAS can help in the diagnosis of PD.
Keimyung Author(s)(Kor)
김정범
Publisher
School of Medicine
Citation
Seon-Cheol Park et al. (2014). Is the Psychotic Depression Assessment Scale a useful diagnostic tool?: The CRESCEND study. Journal of Affective Disorders, 166, 79–85. doi: 10.1016/j.jad.2014.05.004
Type
Article
ISSN
0165-0327
Source
https://www.sciencedirect.com/science/article/pii/S0165032714002766?via%3Dihub
DOI
10.1016/j.jad.2014.05.004
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33938
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Psychiatry (정신건강의학)
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