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Obesity paradox in Korean patients undergoing primary percutaneous coronary intervention in ST-segment elevation myocardial infarction

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Author(s)
Won Yu KangMyung Ho JeongYoung Keun AhnJong Hyun KimShung Chull ChaeYoung Jo KimSeung Ho HurIn Whan SeongTaek Jong HongDong Hoon ChoiMyeong Chan ChoChong Jin KimKi Bae SeungWook Sung ChungYang Soo JangSeung Woon RhaJang Ho BaeJeong Gwan ChoSeung Jung Parkother Korea Acute Myocardial Infarction Registry Investigators
Keimyung Author(s)
Hur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
Journal of Cardiology
Issued Date
2010
Volume
55
Issue
1
Keyword
Acute myocardial infarctionCoronary artery diseaseObesityPrognosis
Abstract
The effect of body mass index (BMI) on outcomes after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) is not well known. In patients registered in the Korean Acute Myocardial Infarction Registry (KAMIR) between November 2005 and November 2007, 3824 STEMI patients who arrived at hospital within 12 h after onset of chest pain and underwent primary PCI were analyzed, and divided into four groups according to their BMI: underweight (BMI < 18.5 kg/m2, n = 129); normal weight (18.5 ≤ BMI < 23.0 kg/m2, n = 1253); overweight (23.0 ≤ BMI < 27.5 kg/m2, n = 1959); and obese (BMI ≥ 27.5 kg/m2, n = 483). In-hospital mortality, revascularization in 1 year, mortality in 1 year, and overall mortality were compared between groups. Overweight and obese group were significantly younger, had normal left ventricular ejection fraction, and were more likely to be men with a higher incidence of hypertension, diabetes, and hyperlipidemia. There were no significant differences in symptom-to-door time and door-to-balloon time between groups. Obese patients had significantly lower in-hospital and overall mortalities. Major adverse cardiac events showed a bimodal pattern. Obese STEMI patients treated with primary PCI were associated with lower mortality, which may be explained by better use of medical treatment, hemodynamic stability, and younger age.
Keimyung Author(s)(Kor)
허승호
Publisher
School of Medicine
Citation
Won Yu Kang et al. (2010). Obesity paradox in Korean patients undergoing primary percutaneous coronary intervention in ST-segment elevation myocardial infarction. Journal of Cardiology, 55(1), 84–91. doi: 10.1016/j.jjcc.2009.10.004
Type
Article
ISSN
0914-5087
Source
http://lps3.linkinghub.elsevier.com.proxy.dsmc.or.kr/retrieve/pii/S0914-5087(09)00278-0
DOI
10.1016/j.jjcc.2009.10.004
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33963
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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