A 70-year-old man presented with left-sided weakness and dysarthria. His brain MRI and magnetic resonance angiography demonstrated acute infarctions in the bilateral middle cerebral artery territories in a setting of agenesis of the right internal carotid artery (ICA) with transcavernous anastomosis, a rare developmental anomaly. In this setting, atherosclerotic disease in the unilateral common carotid artery or ICA can induce acute infarctions in the bilateral anterior circulation.
Eun Joo Lee et al. (2012). Acute infarction in a patient with agenesis of the internal carotid artery and transcavernous anastomosis. Journal of Clinical Neuroscience, 19(4), 597–599. doi: 10.1016/j.jocn.2011.07.034