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Recent Perspective on Coronary Bifurcation Intervention: Statement of the “Bifurcation Club in KOKURA”

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Author(s)
YOSHINOBU MURASATOYUTAKA HIKICHISUNAO NAKAMURAFUMIHIKO KAJIYAKIYOTAKA IWASAKIYOSHIHISA KINOSHITAMASAHIRO YAMAWAKITOSHIRO SHINKESHNICHIRO YAMADATAKEHIRO YAMASHITAGIM-HOOI CHOOCHANG-WOOK NAMYOUNG-HAK KIMNIGEL JEPSONMIROSLAW FERENC
Keimyung Author(s)
Nam, Chang Wook
Department
Dept. of Internal Medicine (내과학)
Journal Title
Journal of Interventional Cardiology
Issued Date
2010
Volume
23
Issue
4
Abstract
The treatment of coronary bifurcation lesion remains a challenging issue even in the drug-eluting stent era. Frequent restenosis and stent thrombosis have been recently shown to be related not only to geometrical gap or stent structural deformation but also to rheological disturbance. Low wall shear stress at the lateral side of the bifurcation is likely to cause atherosclerotic changes due to easy access of the macrophages that induce chemical mediators. The turbulent flow over stent metal may facilitate accumulation of platelets, which results in thrombosis. The jailed strut and excess metal overlap may increase these risks. Since dramatic changes of the coronary flow pattern at the bifurcation are closely related to the genesis of atherosclerosis, future bifurcation intervention technique should be considered to restore the original physiological state as well as the anatomical structure.

This article summarizes the global consensus of the members of the Asian Bifurcation Club and European Bifurcation Club at the KOKURA meeting. It also provides a perspective of basic sciences relating to bifurcation anatomy, physiology, and pathology, in the search for a best strategy for bifurcation intervention.
Keimyung Author(s)(Kor)
남창욱
Publisher
School of Medicine
Citation
YOSHINOBU MURASATO et al. (2010). Recent Perspective on Coronary Bifurcation Intervention: Statement of the “Bifurcation Club in KOKURA.” Journal of Interventional Cardiology, 23(4), 295–304. doi: 10.1111/j.1540-8183.2010.00570.x
Type
Article
ISSN
0896-4327
Source
http://dx.doi.org.proxy.dsmc.or.kr/10.1111/j.1540-8183.2010.00570.x
DOI
10.1111/j.1540-8183.2010.00570.x
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34060
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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