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Bilateral spontaneous pneumothorax during cytotoxic chemotherapy for angiosarcoma of the scalp: a case report

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Author(s)
Chang Hwa LeeKeon Uk ParkDeuk Young NahKyoung Sook Won
Keimyung Author(s)
Won, Kyoung SookPark, Keon Uk
Department
Dept. of Nuclear Medicine (핵의학)
Dept. of Internal Medicine (내과학)
Journal Title
Journal of Korean Medical Science
Issued Date
2003
Volume
18
Issue
2
Keyword
PneumothoraxHemangiosarcomaScalp
Abstract
Spontaneous pneumothorax is a rare manifestation of metastatic lung cancers and described in advanced diseases or during cytotoxic chemotherapy which is manifested by sudden onset of dyspnea. The cause or mechanism of spontaneous pneumothorax has been unknown, as well as the association with site of metastases or type of cancers or side effect of chemotherapeutic drugs has been reported rarely. A 68-yr-old man underwent excision of angiosarcoma of the scalp. Chest radiography did not show any evidence of possible metastatic lung lesion at that time. Therefore, systemic doxorubicin and dacarbazine were given. After nineteen days of chemotherapy, he developed a bilateral spontaneous pneumothorax and palpable cervical lymph nodes. Both parietal and visceral pleura were intact and showed no evidence of metastatic and pathologic lesions on thoracoscopic evaluation. The patient managed with bilateral tube thoracostomy and both lungs were expanded. Lymph nodes became unpalpable during three cycles of the paclitaxel and doxorubicin, however, bilateral lung metastases were developed and progressed despite chemotherapy. The patient died due to respiratory failure after five months. This report underlines that spontaneous pneumothorax can occur as the first manifestation of metastatic angiosarcoma even if imaging studies do not show of a metastatic lesion.
Keimyung Author(s)(Kor)
원경숙
박건욱
Publisher
School of Medicine
Citation
Chang Hwa Lee et al. (2003). Bilateral spontaneous pneumothorax during cytotoxic chemotherapy for angiosarcoma of the scalp: a case report. Journal of Korean Medical Science, 18(2), 277–280. doi: 10.3346/jkms.2003.18.2.277
Type
Article
ISSN
1011-8934
DOI
10.3346/jkms.2003.18.2.277
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34090
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
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