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Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction

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Author(s)
Min Goo LeeMyung Ho JeongYoungkeun AhnShung Chull ChaeSeung Ho HurTaek Jong HongYoung Jo KimIn Whan SeongJei Keon ChaeJay Young RhewIn Ho ChaeMyeong Chan ChoJang Ho BaeSeung Woon RhaChong Jin KimDonghoon ChoiYang Soo JangJunghan YoonWook Sung ChungJeong Gwan ChoKi Bae SeungSeung Jung Park
Keimyung Author(s)
Hur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
Journal of Korean Medical Science
Issued Date
2010
Volume
25
Issue
10
Keyword
Metabolic SyndromePrognosisMyocardial Infarction
Abstract
We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute
myocardial infarction and its effect on clinical outcomes. Employing data from the Korea
Acute Myocardial Infarction Registry, a total of 1,990 patients suffered from acute STelevation
myocardial infarction (STEMI) between November 2005 and December 2006
were categorized according to the National Cholesterol Education Program-Adult
Treatment Panel III criteria of MS. Primary study outcomes included major adverse cardiac
events (MACE) during one-year follow-up. Patients were grouped based on existence of
MS: group I: MS (n=1,182, 777 men, 62.8±12.3 yr); group II: Non-MS (n=808, 675 men,
64.2±13.1 yr). Group I showed lower left ventricular ejection fraction (LVEF) (P=0.005).
There were no differences between two groups in the coronary angiographic findings
except for multivessel involvement (P=0.01). The incidence of in-hospital death was higher
in group I than in group II (P=0.047), but the rates of composite MACE during one-year
clinical follow-up showed no significant differences. Multivariate analysis showed that low
LVEF, old age, MS, low high density lipoprotein cholesterol and multivessel involvement
were associated with high in-hospital death rate. In conclusion, MS is an important
predictor for in-hospital death in patients with STEMI.
Keimyung Author(s)(Kor)
허승호
Publisher
School of Medicine
Citation
Min Goo Lee et al. (2010). Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction. Journal of Korean Medical Science, 25(10), 1456–1461. doi: 10.3346/jkms.2010.25.10.1456
Type
Article
ISSN
1011-8934
DOI
10.3346/jkms.2010.25.10.1456
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34108
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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