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Prevalence and Seroprevalence of Low-Risk Human Papillomavirus in Korean Women

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Author(s)
Min-A KimJin-Kyoung OhBo Wook KimDoobyung ChayDong Choon ParkSeok Mo KimEun-Suk KangJae-Hoon KimChi-Heum ChoHai-Rim ShinKyung Seo
Keimyung Author(s)
Cho, Chi Heum
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
Journal of Korean Medical Science
Issued Date
2012
Volume
27
Issue
8
Keyword
Low-Risk Human PapillomavirusPrevalenceSeroprevalence
Abstract
Little is known about the prevalence and seroprevalence of low-risk human papillomavirus
(HPV) and the risk factors for HPV infection in Korean women. We determined the
prevalence of low-risk HPV among 902 women aged 20-59 yr and the seroprevalence of
low-risk HPV subtypes 6 and 11 among 1,094 women aged 9-59 yr in the general
population. Genital low-risk HPV DNA was assessed by liquid hybridization and polymerase
chain reaction. Antibody titers against HPV 6 and 11 were measured by a multiplexed
competitive luminex technique. The prevalence of genital low-risk HPV was 4.9%. It
reached its highest peak of 10.3% at 20-29 yr of age and a second peak of 3.2% at 50-59
yr of age. The seroprevalence of HPV 6 or 11 was 9.4%. It reached its highest peak of
12.7% at 25-29 yr of age and a second peak of 12.3% at 50-59 yr of age. In multivariable
analysis, the number of lifetime sexual partners and past history of sexually transmitted
diseases were associated with the seroprevalence but not prevalence of HPV. It is suggested
that younger women should receive prophylactic HPV vaccination before they become
sexually active and exposed to HPV in their 20s. This study provides baseline data for
developing HPV vaccination programs and monitoring vaccine efficacy in Korea.
Keimyung Author(s)(Kor)
조치흠
Publisher
School of Medicine
Citation
Min-A Kim et al. (2012). Prevalence and Seroprevalence of Low-Risk Human Papillomavirus in Korean Women. Journal of Korean Medical Science, 27(8), 922–928. doi: 10.3346/jkms.2012.27.8.922
Type
Article
ISSN
1011-8934
DOI
10.3346/jkms.2012.27.8.922
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34118
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
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