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Enhancement of Liver and Pancreas on Late Hepatic Arterial Phase Imaging: Quantitative Comparison Among Multiple Gadolinium-Based Contrast Agents at 1.5 Tesla MRI

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Author(s)
Mateus HernandesBong Soo KimRichard C. SemelkaMi Jeong KimSeong Hyun KimHee Jin Kim
Keimyung Author(s)
Kim, Mi Jeong
Department
Dept. of Radiology (영상의학)
Journal Title
Journal of Magnetic Resonance Imaging
Issued Date
2013
Volume
38
Issue
1
Keyword
gadobenate dimegluminegadoliniummagnetic resonance imagingabdominal imagingGadoxetic acid (Gd-EOB-DTPA)Gadobenate dimeglumine (Gd-BOPTA)Gadopentetate dimeglumine (Gd-DTPA)GadobutrolMR Imagingcomparative studiesliver MRIpancreas MRI
Abstract
Purpose:

To compare enhancement of the liver and pancreas quantitatively on late hepatic arterial phase images among various gadolinium-based contrast agents (GBCAs) at 1.5 Tesla (T) MRI.


Materials and Methods:

Patients underwent consecutive MR studies with the following GBCAs: gadopentetate dimeglumine (0.1 mmol/kg) gadobenate dimeglumine (0.05 mmol/kg), gadoxetic acid, and gadobutrol group. The enhancement of liver and pancreas was evaluated quantitatively on late hepatic arterial phase. Relative pancreas-to-liver enhancement ratio was also calculated.


Results:

Mean % enhancement of the liver and the pancreas was 21.57 and 55.40, and mean relative pancreas to liver enhancement was 2.23. Mean % enhancement of the liver for gadopentetate, gadobenate, gadoxetic, and gadobutrol were 20.4 ± 12.3, 21.7 ± 7.1, 16.2 ± 6.1, 29.1 ± 21.9. Significant difference was observed for % enhancement of liver comparing gadobutrol and gadoxetic (P = 0.048). Mean % enhancement of pancreas for gadopentetate, gadobenate, gadoxetic, and gadobutrol were 53.6 ± 12.6, 60.1 ± 13.7, 52.7 ± 10.6, 54.7 ± 19.5. No significant differences were observed for % enhancement of pancreas (P > 0.05). No significant differences were observed for relative pancreas-to-liver enhancement ratio (P > 0.05).


Conclusion:

Our study describes % enhancement of liver and pancreas using various GBCAs. The data may provide reference material on relaxation properties of GBCAs in vivo
Keimyung Author(s)(Kor)
김미정
Publisher
School of Medicine
Citation
Mateus Hernandes et al. (2013). Enhancement of Liver and Pancreas on Late Hepatic Arterial Phase Imaging: Quantitative Comparison
Among Multiple Gadolinium-Based Contrast Agents at 1.5 Tesla MRI. Journal of Magnetic Resonance Imaging, 38(1), 102–108. doi: 10.1002/jmri.23934
Type
Article
ISSN
1053-1807
Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/jmri.23934
DOI
10.1002/jmri.23934
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34154
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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