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Coronary Stenting (Cordis) Without Anticoagulation

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Author(s)
Seong-Wook ParkSeung-Jung ParkMyeong-Ki HongJae-Joong KimSeung-Yun ChoYang-Soo JangKwon-Bae KimKee-Sik KimDong-Joo OhByung-Hee OhJung-Chaee Kang
Keimyung Author(s)
Kim, Kwon BaeKim, Kee Sik
Department
Dept. of Internal Medicine (내과학)
Journal Title
American Journal of Cardiology
Issued Date
1997
Volume
79
Issue
7
Abstract
We evaluated the effect of antithrombotic regimens on
subacute thrombosis and short-term clinical courses after
successful implantation of the Cordis coronary stent,
which is a flexible, balloon expandable, radiopaque
tantalum stent. Two hundred seventy-five consecutive
patients with 290 lesions were treated with 356 Cordis
stent implantations. According to poststent antithrombotic
regimen, patients were divided into 3 groups; 165
patients with 175 lesions received aspirin 200 mg/day,
ticlopidine 500 mg/day, and warfarin for 1 month
(group 1), 66 patients with 69 lesions received aspirin
and ticlopidine (group 2), and 44 patients with 46 lesions
received aspirin alone (group 3) after successful
Cordis stenting. The overall procedural success rates
were 97.7% in group 1, 98.6% in group 2, and 100%
in group 3. More than 65% of the patients were eligible
for elective stenting. The overall rate of stent thrombosis
was 1.8%: 1.2% in patients assigned to the treatment
with aspirin, ticlopidine, and warfarin; 0% in patients
with aspirin and ticlopidine; and 6.8% in patients assigned
to the treatment with aspirin alone. In conclusion,
the Cordis coronary stent is an effective endovascular
stent in various clinical indications including unstable angina
and acute myocardial infarction. Antiplatelet therapy
using aspirin and ticlopidine after successful Cordis
coronary stenting is a promising alternative to anticoagulation
therapy to overcome the drawbacks of stenting.
However, poststent antithrombotic therapy with aspirin
alone is associated with a significant rate of stent
thrombosis.
Keimyung Author(s)(Kor)
김권배
김기식
Publisher
School of Medicine
Citation
Seong-Wook Park et al. (1997). Coronary Stenting (Cordis) Without Anticoagulation. American Journal of Cardiology, 79(7), 901–904. doi: 10.1016/S0002-9149(97)00017-9
Type
Article
ISSN
0002-9149
Source
https://linkinghub.elsevier.com/retrieve/pii/S0002914997000179
DOI
10.1016/S0002-9149(97)00017-9
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34460
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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