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In vitro antimicrobial effect of the tissue conditioner containing silver nanoparticles

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Author(s)
Ki-Young Nam
Keimyung Author(s)
Nam, Ki Young
Department
Dept. of Dentistry (치과학)
Journal Title
Journal of Advanced Prosthodontics
Issued Date
2011
Volume
3
Issue
1
Keyword
Silver nanoparticlesTissue conditionerAntimicrobial effect
Abstract
PURPOSE. The aim of this study was to identify in vitro antimicrobial activity of the tissue conditioner containing silver nanoparticles on microbial
strains, Staphylococcus aureus, Streptococcus mutans and Candida albicans. MATERIALS AND METHODS. Experimental disc samples
(20.0×3.0 mm) of tissue conditioner (GC Soft-Liner, GC cooperation, Tokyo, Japan) containing 0.1 - 3.0% silver nanoparticles (0%: control)
were fabricated. Samples were placed on separate culture plate dish and microbial suspensions (100 μL) of tested strains were inoculated
then incubated at 37℃. Microbial growth was verified at 24 hrs and 72 hrs and the antimicrobial effects of samples were evaluated as a percentage
of viable cells in withdrawn suspension (100 μL). Data were recorded as the mean of three colony forming unit (CFU) numerations
and the borderline of the antimicrobial effect was determined at 0.1% viable cells. RESULTS. A 0.1% silver nanoparticles combined to tissue
conditioner displayed minimal bactericidal effect against Staphylococcus aureus and Streptococcus mutans strains, a 0.5% for fungal
strain. Control group did not show any microbial inhibitory effect and there were no statistical difference between 24 hrs and extended 72 hrs
incubation time (P > .05). CONCLUSION. Within the limitation of this in vitro study, the results suggest that the tissue conditioner containing
silver nanoparticles could be an antimicrobial dental material in denture plaque control. Further mechanical stability and toxicity studies are still
required. [J Adv Prosthodont 2011;3:20-4] KEY WORDS. Silver nanoparticles, Tissue conditioner, Antimicrobial effect
Keimyung Author(s)(Kor)
남기영
Publisher
School of Medicine
Citation
Ki-Young Nam. (2011). In vitro antimicrobial effect of the tissue conditioner containing silver nanoparticles. Journal of Advanced Prosthodontics, 3(1), 20–24. doi: 10.4047/jap.2011.3.1.20
Type
Article
ISSN
2005-7806
DOI
10.4047/jap.2011.3.1.20
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34480
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dentistry (치과학)
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