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A Successful Live Birth Through in vitro Fertilization Program After Conservative Treatment of FIGO Grade I Endometrial Cancer

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Author(s)
Joon-Cheol ParkChi-Hum ChoJeong-Ho Rhee
Keimyung Author(s)
Park, Joon CheolCho, Chi HeumRhee, Jeong Ho
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
Journal of Korean Medical Science
Issued Date
2006
Volume
21
Issue
3
Keyword
Endometrial NeoplasmsFertilization in VitroProgestins
Abstract
Infertile women with chronic anovulation are prone to be exposed to unopposed
estrogen stimulation and have the high risk of being suffering from endometrial
hyperplasia or even endometrial carcinoma. A few reports have suggested that
nulliparous young women (under 40 yr of age) with endometrial carcinoma could
be treated conservatively to preserve fertility and succeed the live birth. We report
on a 36-yr-old woman who received conservative treatment of endometrial carcinoma
(stage I, grade 1) by curettage and progestin. After megestrol medication of
total 71,680 mg during 24 weeks, we found the regression of endometrial lesion by
curettage and hysteroscopic examination. Then we decided to perform in vitro fertilization
program. Two embryos were transferred and heterotypic pregnancy was
diagnosed 27 days after embryo transfer. After right salpingectomy, she received
routine obstetrical care and delivered by cesarean section at 38 weeks in gestational
periods. Two years after delivery, she is healthy without any evidence of recurrent
disease. The fertility preserving treatment is an option in endometrial cancer patients
if carefully selected, and assisted reproductive technologies would be helpful.
Key Words : Endometrial Neoplasms; Fertilization in Vitro; Progestins
Keimyung Author(s)(Kor)
박준철
조치흠
이정호
Publisher
School of Medicine
Citation
Joon-Cheol Park et al. (2006). A Successful Live Birth Through in vitro Fertilization Program After Conservative Treatment of FIGO Grade I Endometrial Cancer. Journal of Korean Medical Science, 21(3), 567–571. doi: 10.3346/jkms.2006.21.3.567
Type
Article
ISSN
1011-8934
DOI
10.3346/jkms.2006.21.3.567
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34521
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
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