계명대학교 의학도서관 Repository

The Risk Factors and Outcome of Acute Kidney Injury in the Intensive Care Units

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Author(s)
Woo Young ParkEun Ah HwangMi Hyun JangSung Bae ParkHyun Chul Kim
Keimyung Author(s)
Park, Woo YoungHwang, Eun AhPark, Sung BaeKim, Hyun Chul
Department
Dept. of Internal Medicine (내과학)
Journal Title
Korean Journal of Internal Medicine
Issued Date
2010
Volume
25
Issue
2
Keyword
Kidney failureIntensive care unitsRisk factors
Abstract
Background/Aims

Acute kidney injury (AKI) is a common and serious complication in critically ill patients, especially in the intensive care unit (ICU). The present study was performed to evaluate the occurrence rate of AKI using the RIFLE (increasing severity classes risk, injury, and failure, and the two outcome classes loss and end-stage kidney disease) classification, to define factors associated with AKI and hospital mortality.


Methods

We performed a retrospective study of all ICU patients over a 6-month period at Keimyung University Dongsan Hospital, Daegu, Korea. AKI was evaluated according to the RIFLE classification.


Results

AKI occurred in 156 of the 378 patients (41.3%) during their ICU stay, with maximum RIFLE-R, I, and F in 13.8%, 12.4%, and 15.1%, respectively. In univariate analysis, the proportion of medical admission and maximum Sequential Organ Failure Assessment (SOFA) score (SOFAmax) were significantly higher in patients with AKI than in those without. However, these factors did not remain significant in a multivariate analysis. The overall mortality rate of ICU patients was 25.7%. In multivariate analysis, mean age, occurrence of AKI, SOFAmax score, pulmonary disease, and malignancy were independent risk factors for hospital mortality.


Conclusions

In these ICU patients, AKI is associated with increased hospital mortality. The RIFLE classification is a simple and useful clinical tool to detect and stratify the severity of AKI, and may aid in the prediction of outcome.

Keywords: Kidney failure, Intensive care units, Risk factors
Keimyung Author(s)(Kor)
박우영
황은아
박성배
김현철
Publisher
School of Medicine
Citation
Woo Young Park et al. (2010). The Risk Factors and Outcome of Acute Kidney Injury in the Intensive Care Units. Korean Journal of Internal Medicine, 25(2), 181–187. doi: 10.3904/kjim.2010.25.2.181
Type
Article
ISSN
1226-3303
DOI
10.3904/kjim.2010.25.2.181
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34580
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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