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신이식 후 발생한 십이지장 림프세포증식질환 1예

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Author(s)
곽진호진규복김정은황은아한승엽박성배김현철
Keimyung Author(s)
Han, Seung YeupPark, Sung BaeJin, Kyu BokKim, Hyun ChulHwang, Eun Ah
Department
Dept. of Internal Medicine (내과학)
Kidney Institute (신장연구소)
Journal Title
Korean Journal of Nephrology
Issued Date
2007
Volume
26
Issue
2
Keyword
Lymphoproliferative disorderKidney transplantationDuodenum
Abstract
Posttransplant lymphoproliferative disorder (PTLD) is an uncommon but life-threatening complication of immunosuppressive therapy following solid organ transplantation. It encompasses a heterogeneous group of lymphoproliferative disorders ranging from reactive, polyclonal hyperplasia to aggressive non-Hodgkin`s lymphoma. The majority of PTLD is of B-cell origin and associated with Epstein-Barr virus (EBV) infection. Gastrointestinal involvement, especially small bowel and colon, is common in patients with PTLD, but the duodenum is rarely involved. We have experienced a case of PTLD involving the duodenum eight years after kidney transplantation in 50-year-old man. Two weeks before admission, he had complained of epigastric pain, and was diagnosed as pangastritis and duodenal ulcer by upper gastrointestinal endoscopy. He was admitted due to aggravated epigastric pain despite anti-ulcer medication. On the seventh hospital day, we found a new mass-like lesion in the pyloric area of antrum and diffuse ulceration in the duodenum by follow-up endoscopy. Histologic findings revealed diffuse large B-cell lymphoma. During reduction in immunosuppressive regimens, his conditions deteriorated rapidly. He died of sepsis associated with duodenal ulcer perforation, 18 days after diagnosis. Key Words : Lymphoproliferative disorder, Kidney transplantation, Duodenum
Alternative Title
A Case of Posttransplant Lymphoproliferative Disorder in the Duodenum after Kidney Transplantation
Keimyung Author(s)(Kor)
황은아
한승엽
박성배
진규복
김현철
Publisher
School of Medicine
Citation
곽진호 et al. (2007). 신이식 후 발생한 십이지장 림프세포증식질환 1예. Korean Journal of Nephrology, 26(2), 294~299-294~299.
Type
Article
ISSN
1975-9460
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34593
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
3. Research Institutues (연구소) > Kidney Institute (신장연구소)
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