계명대학교 의학도서관 Repository

The Comparison of Mydriatic Effect Between Two Drugs of Different Mechanism

Metadata Downloads
Author(s)
Ji-Hyun ParkYoung-Chun LeeSe-Youp Lee
Keimyung Author(s)
Lee, Se Youp
Department
Dept. of Ophthalmology (안과학)
Journal Title
Korean Journal of Ophthalmology
Issued Date
2009
Volume
23
Issue
1
Keyword
Pupil dilation1% tropicamide2.5% phenylephrine
Abstract
Purpose

To maximize effective use of mydriatic drugs through comparing the pupillary dilation effects between 1% tropicamide and 2.5% phenylephrine.


Methods

Fifty people requiring pupillary dilation were divided into 3 groups. Group 1 was treated with one drop of 1% tropicamide in the right eye and one drop of 2.5% phenylephrine in the left eye. Group 2 was treated twice during a 5-minute interval with 1% tropicamide in the right eye. Group 3 was treated twice during a 5-minute interval with 2.5% phenylephrine in the right eye. Groups 2 and 3 were treated with 2.5% phenylephrine and 1% tropicamide in the left eye, administered during a 5-minute interval. The pupillary size was measured in all groups for 40 minutes following eye drops administration.


Results

The mean patient age was 15.7 years. Group 1 included 10 patients, and groups 2 and 3 included 20 patients each. Eight patients in group 1 and 16 patients in group 2 developed a larger right pupil. Fourteen patients in group 3 developed a larger left pupil.


Conclusions

Our study showed that 1% tropicamide, with its parasympathetic antagonistic mechanism of action, was more effective at inducing pupillary dilation than 2.5% phenylephrine, and the combination of 1% tropicamide and 2.5% phenylephrine was more effective than multiple drops of single eye drops.

Keywords: Pupil dilation, 1% tropicamide, 2.5% phenylephrine
Keimyung Author(s)(Kor)
이세엽
Publisher
School of Medicine
Citation
Ji-Hyun Park et al. (2009). The Comparison of Mydriatic Effect Between Two Drugs of Different Mechanism. Korean Journal of Ophthalmology, 23(1), 40–42. doi: 10.3341/kjo.2009.23.1.40
Type
Article
ISSN
1011-8942
DOI
10.3341/kjo.2009.23.1.40
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34633
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Ophthalmology (안과학)
Authorize & License
  • Authorize공개
Files in This Item:

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.