Correlation Between Banff Classification Acute Rejection Scores and Reversal of Rejection

Abstract

RENAL biopsies play a critical role in the management of transplant recipients. Recently, an international working group issued a schema for the standardization of allograft biopsy interpretation. 1 The Banff classification of acute rejection is based on histologic grades and scores for borderline changes, and glomerular, vascular, interstitial, and tubular lesions. The aim was to examine whether the Banff classification accurately differentiates clinically rele- vant grades of rejection. In addition, the clinical outcome of these rejection episodes was correlated to the pathologic grading and scoring of the biopsies.