Effect of Modified Polyhemoglobin on the Ischemia/Reperfusion Injury in Kidney
- Affiliated Author(s)
- 문교철; 곽춘식; 김상표; 박성배; 김현철; 김여희
- Alternative Author(s)
- Park, Sung Bae; Kim, Hyun Chul; Kim, You Hee; Mun, Kyo Cheol; Kwak, Chun Sik; Kim, Sang Pyo
- Journal Title
- Transplantation Proceedings
- ISSN
- 0041-1345
- Issued Date
- 2003
- Abstract
- DURING TRANSPLANTATION the kidney suffers an
ischemia/reperfusion injury.¹,²
Reactive oxygen spe-
cies generated by xanthine oxidase during reperfusion of
the ischemic kidney may be in par responsible for the renal
injury.¹,²
Oxygen free radicals are removed by antioxidant
enzymes such as superoxide dismutase (SOD), catalase, and
glutathione peroxidase.³
Using glutaraldehyde we sought to
cross-link hemoglobin containing SOD and catalase to
protect the kidney from an ischemia/reperfusion injury
during transplantation.
- 공개 및 라이선스
-
- 파일 목록
-
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.