Effect of Modified Polyhemoglobin on the Ischemia/Reperfusion Injury in Kidney
- Keimyung Author(s)
- Park, Sung Bae; Kim, Hyun Chul; Kim, You Hee; Mun, Kyo Cheol; Kwak, Chun Sik; Kim, Sang Pyo
- Department
- Kidney Institute (신장연구소)
Dept. of Pathology (병리학)
Dept. of Biochemistry (생화학)
Dept. of Internal Medicine (내과학)
- Journal Title
- Transplantation Proceedings
- Issued Date
- 2003
- Volume
- 35
- Issue
- 1
- Abstract
- DURING TRANSPLANTATION the kidney suffers an
ischemia/reperfusion injury.¹,²
Reactive oxygen spe-
cies generated by xanthine oxidase during reperfusion of
the ischemic kidney may be in par responsible for the renal
injury.¹,²
Oxygen free radicals are removed by antioxidant
enzymes such as superoxide dismutase (SOD), catalase, and
glutathione peroxidase.³
Using glutaraldehyde we sought to
cross-link hemoglobin containing SOD and catalase to
protect the kidney from an ischemia/reperfusion injury
during transplantation.
- Publisher
- School of Medicine
- Citation
- K.C. Mun et al. (2003). Effect of Modified Polyhemoglobin on the Ischemia/Reperfusion Injury in Kidney. Transplantation Proceedings, 35(1), 99–100. doi: 10.1016/S0041-1345(02)03766-1
- Type
- Article
- ISSN
- 0041-1345
- Source
- https://www.sciencedirect.com/science/article/pii/S0041134502037661?via%3Dihub
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