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Effect of Modified Polyhemoglobin on the Ischemia/Reperfusion Injury in Kidney

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Author(s)
K.C. MunH.-G. LeeT.H. LeeY.-H. KimC.S. KwakS.P. KimE.J. ChangS.-B. ParkH.C. Kim
Keimyung Author(s)
Park, Sung BaeKim, Hyun ChulKim, You HeeMun, Kyo CheolKwak, Chun SikKim, Sang Pyo
Department
Kidney Institute (신장연구소)
Dept. of Pathology (병리학)
Dept. of Biochemistry (생화학)
Dept. of Internal Medicine (내과학)
Journal Title
Transplantation Proceedings
Issued Date
2003
Volume
35
Issue
1
Abstract
DURING TRANSPLANTATION the kidney suffers an
ischemia/reperfusion injury.¹,²
Reactive oxygen spe-
cies generated by xanthine oxidase during reperfusion of
the ischemic kidney may be in par responsible for the renal
injury.¹,²
Oxygen free radicals are removed by antioxidant
enzymes such as superoxide dismutase (SOD), catalase, and
glutathione peroxidase.³
Using glutaraldehyde we sought to
cross-link hemoglobin containing SOD and catalase to
protect the kidney from an ischemia/reperfusion injury
during transplantation.
Keimyung Author(s)(Kor)
문교철
곽춘식
김상표
박성배
김현철
김여희
Publisher
School of Medicine
Citation
K.C. Mun et al. (2003). Effect of Modified Polyhemoglobin on the Ischemia/Reperfusion Injury in Kidney. Transplantation Proceedings, 35(1), 99–100. doi: 10.1016/S0041-1345(02)03766-1
Type
Article
ISSN
0041-1345
Source
https://www.sciencedirect.com/science/article/pii/S0041134502037661?via%3Dihub
DOI
10.1016/S0041-1345(02)03766-1
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34706
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Biochemistry (생화학)
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
3. Research Institutues (연구소) > Kidney Institute (신장연구소)
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