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Does the Mean Arterial Pressure Influence Mortality Rate in Patients with Acute Hypoxemic Respiratory Failure under Mechanical Ventilation?

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Author(s)
Juarda GjonbratajHyun Jung KimHye In JungWon-Il Choi
Keimyung Author(s)
Choi, Won Il
Department
Dept. of Internal Medicine (내과학)
Journal Title
Tuberculosis and Respiratory Diseases
Issued Date
2015
Volume
78
Issue
2
Keyword
Arterial PressureRespiratory InsufficiencyRespirationArtificial
Abstract
Background: In sepsis patients, target mean arterial pressures (MAPs) greater than 65 mm Hg are recommended.
However, there is no such recommendation for patients receiving mechanical ventilation. We aimed to evaluate the
influence of MAP over the first 24 hours after intensive care unit (ICU) admission on the mortality rate at 60 days post-
admission in patients showing acute hypoxemic respiratory failure under mechanical ventilation.
Methods: This prospective, multicenter study included 22 ICUs and compared the mortality and clinical outcomes in
patients showing acute hypoxemic respiratory failure with high (75–90 mm Hg) and low (65–74.9 mm Hg) MAPs over
the first 24 hours of admission to the ICU.
Results: Of the 844 patients with acute hypoxemic respiratory failure, 338 had a sustained MAP of 65–90 mm Hg over
the first 24 hours of admission to the ICU. At 60 days, the mortality rates in the low (26.2%) and high (24.5%) MAP groups
were not significantly different. The ICU days, hospital days, and 60-day mortality rate did not differ between the groups.
Conclusion: In the first 24 hours of ICU admission, MAP range between 65 and 90 mm Hg in patients with acute
hypoxemic respiratory failure under mechanical ventilation may not cause significantly differences in 60-day mortality.
Keywords: Arterial Pressure; Respiratory Insufficiency; Respiration, Artificial
Keimyung Author(s)(Kor)
최원일
Publisher
School of Medicine
Citation
Juarda Gjonbrataj et al. (2015). Does the Mean Arterial Pressure Influence Mortality Rate in Patients
with Acute Hypoxemic Respiratory Failure under Mechanical Ventilation? Tuberculosis and Respiratory Diseases, 78(2), 85–91. doi: 10.4046/trd.2015.78.2.85
Type
Article
ISSN
1738-3536
DOI
10.4046/trd.2015.78.2.85
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34777
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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