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Prognostic Value of the Age, Creatinine, and Ejection Fraction Score for 1-Year Mortality in 30-Day Survivors Who Underwent Percutaneous Coronary Intervention After Acute Myocardial Infarction

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Author(s)
Jang Hoon LeeMyung Hwan BaeDong Heon YangHun Sik ParkYongkeun ChoMyung Ho JeongYoung Jo KimKee-Sik KimSeung Ho HurIn Whan SeongMyeong Chan ChoChong Jin KimShung Chull Chae
Keimyung Author(s)
Hur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
American Journal of Cardiology
Issued Date
2015
Volume
115
Issue
9
Abstract
Few simple and effective tools are available for determining the prognosis of 30-day
survivors after acute myocardial infarction. We aimed to assess whether the simple age,
creatinine, and ejection fraction (ACEF) score could predict 1-year mortality of 12,000 poste
myocardial infarction 30-day survivors who underwent percutaneous coronary intervention.
The ACEF score was computed as follows: (age/ejection fraction) D 1, if the serum
creatinine was >2 mg/dl. Accuracy was defined through receiver-operating characteristics
analysis and area under the curve (AUC) evaluation. Twelve risk factors were selected
and ranked according to their AUC value. Age, ejection fraction, and serum creatinine
levels indicated the best AUC value. The ACEF score was significantly higher in the nonsurvivors
(1.95 – 0.82 vs 1.28 – 0.50; p <0.001) and was an independent predictor of 1-year
mortality (adjusted hazard ratio 2.26; p <0.001). The best accuracy was achieved by a
prediction model including 12 risk factors (AUC[ 0.80), but this did not significantly differ
compared with the AUC (0.79) of the ACEF score (p [ ns). Adjusted hazard ratios for
1-year mortality were 1 (reference), 3.11 (p <0.001), and 10.38 (p <0.001) for the ACEFLOW
(ACEF score <1.0), ACEFMID (ACEF score 1.0 to 1.39), and ACEFHIGH (ACEF score ‡1.4)
groups, respectively. The ACEF score may be a novel valid model to stratify the 1-year
mortality risk in 30-day survivors who underwent percutaneous coronary intervention
after acute myocardial infarction. 2015 Elsevier Inc. All rights reserved. (Am J Cardiol
2015;115:1167e1173)
Keimyung Author(s)(Kor)
허승호
Publisher
School of Medicine
Citation
Jang Hoon Lee et al. (2015). Prognostic Value of the Age, Creatinine, and Ejection Fraction Score for 1-Year Mortality in 30-Day Survivors Who Underwent Percutaneous Coronary Intervention After Acute Myocardial Infarction. American Journal of Cardiology, 115(9), 1167–1173. doi: 10.1016/j.amjcard.2015.02.001
Type
Article
ISSN
0002-9149
Source
https://linkinghub.elsevier.com/retrieve/pii/S0002914915006864
DOI
10.1016/j.amjcard.2015.02.001
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34895
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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