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Relation of Fractional Flow Reserve After Drug-Eluting Stent Implantation to One-Year Outcomes

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Author(s)
William F. FearonChang-Wook NamSeung-Ho HurYun-Kyeong ChoHyoung-Seob ParkHyuck-Jun YoonHyungseop KimIn-Sung ChungYoon-Nyun KimKwon-Bae KimJoon-HyungBon-Kwon KooSeung-Jea Tahk
Keimyung Author(s)
Nam, Chang WookHur, Seung HoCho, Yun KyeongPark, Hyoung SeobYoon, Hyuck JunKim, Hyung SeopKim, Yoon NyunKim, Kwon BaeChung, In Sung
Department
Dept. of Internal Medicine (내과학)
Dept. of Preventive Medicine (예방의학)
Journal Title
American Journal of Cardiology
Issued Date
2011
Volume
107
Issue
12
Abstract
Patients still present with drug-eluting stent (DES) failure despite an angiographically
successful implantation. The aim of the present study was to investigate the relation
between the fractional flow reserve (FFR) measured after DES implantation and the
clinical outcomes at 1 year. A total of 80 patients (mean age 62 years, 74% men, 99 DESs)
underwent coronary pressure measurement at maximum hyperemia after successful DES
implantation. The composite of major adverse cardiac events (MACE), including death,
myocardial infarction, and ischemia-driven target vessel revascularization was evaluated at
1 year. The patients were divided into 2 groups (low-FFR group, FFR <0.90 and high-FFR
group, FFR >0.90) according to the median FFR. The mean poststent percent diameter
stenosis was 11 5% in the low-FFR group and 12 3% in the high-FFR group (p 0.31).
Left anterior descending coronary artery lesions were more frequent in the low-FFR group
than in the high-FFR group (82% vs 55%, p 0.02). The mean stent length was greater in
the low-FFR group than in the high-FFR group (38 18 vs 28 13 mm, p 0.01). Six
cases (7.5%) of MACE occurred during the 1-year follow-up. The rate of MACE was
12.5% in the low-FFR group and 2.5% in the high-FFR group (p <0.01). Receiver
operating characteristic curves revealed 0.90 as the best cutoff of FFR after DES
implantation for the prediction of 1-year MACE. In conclusion, a poststent FFR of
<0.90 correlated with a greater adverse event rate at 1 year. © 2011 Published by
Elsevier Inc. (Am J Cardiol 2011;107:1763–1767)
Keimyung Author(s)(Kor)
남창욱
허승호
조윤경
박형섭
윤혁준
김형섭
김윤년
김권배
정인성
Publisher
School of Medicine
Citation
William F. Fearon et al. (2011). Relation of Fractional Flow Reserve After Drug-Eluting Stent Implantation to One-Year Outcomes. American Journal of Cardiology, 107(12), 1763–1767. doi: 10.1016/j.amjcard.2011.02.329
Type
Article
ISSN
0002-9149
Source
https://linkinghub.elsevier.com/retrieve/pii/S0002914911010186
DOI
10.1016/j.amjcard.2011.02.329
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34896
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학)
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