Hospital Discharge Risk Score System for the Assessment of Clinical Outcomes in Patients with Acute Myocardial Infarction (Korea Acute Myocardial Infarction Registry [KAMIR] Score)
- Author(s)
- Hyun Kuk Kim; Myung Ho Jeong; Youngkeun Ahn; Jong Hyun Kim; Shung Chull Chae; Young Jo Kim; Seung Ho Hur; In Whan Seong; Taek Jong Hong; Dong Hoon Choi; Myeong Chan Cho; Chong Jin Kim; Ki Bae Seung; Wook Sung Chung; Yang Soo Jang; Seung Woon Rha; Jang Ho Bae; Jeong Gwan Cho; Seung Jung Park
- Keimyung Author(s)
- Hur, Seung Ho
- Department
- Dept. of Internal Medicine (내과학)
- Journal Title
- American Journal of Cardiology
- Issued Date
- 2011
- Volume
- 107
- Issue
- 7
- Abstract
- Assessment of risk at time of discharge could be a useful tool for guiding postdischarge
management. The aim of this study was to develop a novel and simple assessment tool for
better hospital discharge risk stratification. The study included 3,997 hospital-discharged
patients with acute myocardial infarction who were enrolled in the nationwide prospective
Korea Acute Myocardial Infarction Registry-1 (KAMIR-1) from November 2005 through
December 2006. The new risk score system was tested in 1,461 hospital-discharged patients
who were admitted from January 2007 through January 2008 (KAMIR-2). The new risk
score system was compared to the Global Registry of Acute Coronary Events (GRACE)
postdischarge risk model during a 12-month clinical follow-up. During 1-year follow-up,
all-cause death occurred in 228 patients (5.7%) and 81 patients (5.5%) in the development
and validation cohorts, respectively. The new risk score (KAMIR score) was constructed
using 6 independent variables related to the primary end point using a multivariable Cox
regression analysis: age, Killip class, serum creatinine, no in-hospital percutaneous coronary
intervention, left ventricular ejection fraction, and admission glucose based on multivariate-
adjusted risk relation. The KAMIR score demonstrated significant differences in
its predictive accuracy for 1-year mortality compared to the GRACE score for the developmental
and validation cohorts. In conclusion, the KAMIR score for patients with acute
myocardial infarction is a simpler and better risk scoring system than the GRACE hospital
discharge risk model in prediction of 1-year mortality. © 2011 Elsevier Inc. All rights
reserved. (Am J Cardiol 2011;107:965–971)
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