계명대학교 의학도서관 Repository

Expression of Basement Membrane Gene in Cultured Skin Fibroblasts from Patients with Diabetes Mellitus

Metadata Downloads
Author(s)
Byung Chun KimKyu Suk Lee
Keimyung Author(s)
Kim, Byung ChunLee, Kyu Suk
Department
Dept. of Dermatology (피부과학)
Journal Title
Annals of Dermatology
Issued Date
1996
Volume
8
Issue
1
Abstract
Background: Bullous eruption of diabetes(BD) is a rare cutaneous sign of diabetes melli- tus(DM). The mechwism for the development of these lesions is unknown, although speculation has ranged from trauma to vascular insufficiency. Objectwe: Our purpose is to evaluate the diRerence of basement membrane gene expression in cultured skin fibroblasts between patients with diabetes and normal controls. Methods: TataI RKA was extracted kom cultured skin fibroblasts of DM and normal, and then Northern blot and slot-blot hybridixations were done. Resaalts: The mRNA levels of a(I) procoUagen, c(IV) procollagen, 6bronectin, and laminin Bl were not altered significantly in the DM. Conclusion: Our results suggest that BB has na relevance to the alteration of basement membrane components. Further studies are needed to clarify the underlying pathogenic mechanism of BD. (Ann Dermatol 8:(1) 1-5, 1996).
Keimyung Author(s)(Kor)
김병천
이규석
Publisher
School of Medicine
Citation
Byung Chun Kim and Kyu Suk Lee. (1996). Expression of Basement Membrane Gene in Cultured Skin Fibroblasts from Patients with Diabetes Mellitus. Annals of Dermatology, 8(1), 1–5.
Type
Article
ISSN
1013-9090
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34996
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.