계명대학교 의학도서관 Repository

Prognostic factors in FIGO stage IB-IIA small cell neuroendocrine carcinoma of the uterine cervix treated surgically: results of a multi-center retrospective Korean study

Metadata Downloads
Author(s)
J.-M. LeeK.-B. LeeJ.-H. NamS.-Y. RyuD.-S. BaeJ.-T. ParkS.-C. KimS.-D. ChaK.-R. KimS.-Y. SongS.-B. Kang
Keimyung Author(s)
Cha, Soon Do
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
Annals of Oncology
Issued Date
2008
Volume
19
Issue
2
Abstract
Background: To determine the clinical and pathologic prognostic factors in surgically treated patients with
International Federation of Gynecology and Obstetrics (FIGO) stage IB–IIA small cell neuroendocrine carcinoma of the
uterine cervix (SCNEC).
Patients and methods: We retrospectively reviewed a total of 68 patients with FIGO stage IB–IIA SCNEC surgically
treated from January 1997 to December 2003 in Korea.
Results: Of the 68 patients, 43 had FIGO stage IB1 SCNEC, 15 had stage IB2, and 10 had stage IIA. Seven were
treated with radical surgery alone; 11 with neoadjuvant chemotherapy (NACT) followed by radical surgery; 24 with
radical surgery followed by adjuvant chemotherapy; and 26 with radical surgery followed by adjuvant radiation or
chemoradiation. After a median follow-up of 44 months (range, 6–113 months), the 2-year and 5-year survival rates for
all patients were 64.6% and 46.6%, respectively. Univariate and multivariate analysis showed that FIGO stage was
predictive of poor prognosis. Patients who received NACT showed poorer prognosis than those who did not receive
NACT. Adjuvant chemoradiation did not improve survival compared with adjuvant chemotherapy alone.
Conclusions: FIGO stage may act as a surrogate for factors prognostic of survival. Primary radical surgery followed
by adjuvant chemotherapy is the preferred treatment modality for patients with early stage SCNEC.
Key words: neuroendocrine carcinoma, prognosis, small cell, uterine cervix
Keimyung Author(s)(Kor)
차순도
Publisher
School of Medicine
Citation
J.-M. Lee et al. (2008). Prognostic factors in FIGO stage IB-IIA small cell neuroendocrine carcinoma of the uterine cervix treated surgically: results of a multi-center retrospective Korean study. Annals of Oncology, 19(2), 321–326. doi: 10.1093/annonc/mdm465
Type
Article
ISSN
0923-7534
Source
http://lps3.academic.oup.com.proxy.dsmc.or.kr/annonc/article-lookup/doi/10.1093/annonc/mdm465
DOI
10.1093/annonc/mdm465
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35015
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.