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Male predominance of pneumonia and hospitalization in pandemic influenza A (H1N1) 2009 infection

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Author(s)
Won-Il ChoiByung Hak RhoMi-Young Lee
Keimyung Author(s)
Choi, Won IlRho, Byung HakLee, Mi Young
Department
Dept. of Internal Medicine (내과학)
Dept. of Radiology (영상의학)
Dept. of Preventive Medicine (예방의학)
Journal Title
BMC Research Notes
Issued Date
2011
Volume
4
Issue
1
Abstract
BACKGROUND:
Pandemic influenza A (H1N1) disproportionately affects different age groups. The purpose of the current study was to describe the age and gender difference of pandemic influenza A (H1N1) cases that lead to pneumonia, hospitalization or ICU admission.

METHODS:
Data were collected retrospectively between May 2009 and December 2009. All of the diagnoses of H1N1 were confirmed by real-time reverse-transcription polymerase chain reaction (RT-PCR).

RESULTS:
During the study period there were 3402 cases of RT-PCR positive H1N1, among which 1812 were males and 1626 were adults (> 15 years of age). 6% (206/3402) of patients required hospitalization, 3.6% (122/3402) had infiltrates on chest radiographs, and 0.70% (24/3402) were admitted to intensive care unit (ICU). The overall fatality rate was 0.1% (4/3402). The rate of hospitalization was sharply increased in patients ≥ 50 years of age especially in male. Out of 122 pneumonia patients, 68.8% (84 patients) were male. Among the patients admitted to the ICU, 70.8% (17 patients) were male. Approximately 1 of 10 H1N1-infected patients admitted to the ICU were ≥ 70 years of age.

CONCLUSIONS:
Among the confirmed cases of H1N1, the ICU admission rate was < 1% and the case fatality rate was 0.1%. Male had a significantly higher rate of pneumonia and hospital admission. These findings should be taken into consideration when developing vaccination and treatment strategies.
Keimyung Author(s)(Kor)
최원일
노병학
이미영
Publisher
School of Medicine
Citation
Won-Il Choi et al. (2011). Male predominance of pneumonia and hospitalization in pandemic influenza A (H1N1) 2009 infection. BMC Research Notes, 4(1), 351–351. doi: 10.1186/1756-0500-4-351
Type
Article
ISSN
1756-0500
DOI
10.1186/1756-0500-4-351
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35251
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학)
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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