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Comparison of Paclitaxel-, Sirolimus-, and Zotarolimus-Eluting Stents in Patients With Acute ST-Segment Elevation Myocardial Infarction and Metabolic Syndrome

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Author(s)
Min Goo LeeMyung Ho JeongYoungkeun AhnJeong Gwan ChoJong Chun ParkJung Chaee KangShung Chull ChaeSeung Ho HurTaek Jong HongYoung Jo KimIn Whan SeongJei Keon ChaeJay Young RhewIn Ho ChaeMyeong Chan ChoJang Ho BaeSeung Woon RhaChong Jin KimDonghoon ChoiYang Soo JangJunghan YoonWook Sung ChungKi Bae SeungSeung Jung Park
Keimyung Author(s)
Hur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
Circulation Journal
Issued Date
2011
Volume
75
Issue
9
Abstract
Background: The purpose of the present study was to compare the efficacy and safety of paclitaxel-eluting stent (PES), sirolimus-eluting stent (SES), and zotarolimus-eluting stent (ZES) in primary percutaneous coronary intervention (PCI) for acute ST-segment elevation myocardial infarction (STEMI) with metabolic syndrome (MS). Methods and Results: Using data from Korea Acute Myocardial Infarction Registry (KAMIR; November 2005-December 2007), a total of 1,768 MS patients with STEMI who underwent primary PCI were enrolled: The PES group was 634, SES group, 906, and ZES group, 228. The primary endpoint was major adverse cardiac event (all-cause death, re-myocardial infarction, target lesion revascularization) during 12 months follow-up. At 12 months, the cumulative incidence of primary endpoint in the PES, SES, and ZES groups was 10.9%, 9.1%, and 11.0%, respectively (P=0.086). Incidence of death, recurrent myocardial infarction, or target lesion revascularization did not differ among the 3 groups. There were 7 episodes of acute (0.3% in PES group, 0.4% in SES group, and 0.4% in ZES group, respectively, P=0.773) and 18 episodes of cumulative stent thrombosis including late stent thrombosis (0.9% in PES group, 1.0% in SES group, and 1.3% in ZES group, respectively, P=0.448). Conclusions: Implantation of SES, PES, and ZES in MS patients with STEMI undergoing primary PCI provided comparable clinical outcomes in patients enrolled in KAMIR.
Keimyung Author(s)(Kor)
허승호
Publisher
School of Medicine
Citation
Min Goo Lee et al. (2011). Comparison of Paclitaxel-, Sirolimus-, and Zotarolimus-Eluting Stents in Patients With Acute ST-Segment Elevation Myocardial Infarction and Metabolic Syndrome. Circulation Journal, 75(9), 2120–2127. doi: 10.1253/circj.CJ-11-0263
Type
Article
ISSN
1346-9843
DOI
10.1253/circj.CJ-11-0263
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35414
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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