계명대학교 의학도서관 Repository

Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction

Metadata Downloads
Affiliated Author(s)
남창욱
Alternative Author(s)
Nam, Chang Wook
Journal Title
Circulation Journal
ISSN
1346-9843
Issued Date
2010
Abstract
Background: The characteristics of the periodic variation in acute myocardial infarction (AMI) and the subsequent effect on management and prognosis have not been fully investigated in a large number of Asian populations. Methods and Results: From a prospective, observational multicenter online registry, 4,573 patients diagnosed as AMI in Korea from January to December 2006 were included. The highest incidence of AMI was between 8 a.m. and noon. The number of cases was highest in the winter and lowest in the autumn (13.6 vs 11.4 patients per day, P<0.001). Patients with symptom onset during working hours had a shorter time to first medical contact (203±288 min) compared with out-of-hours onset (230±288 min, P=0.003). In patients who underwent primary angioplasty, out-of hours symptom onset was associated with a greater time delay in both the patient's and the medical facility's response (door-to-balloon time out-of hours vs working hours: 101±54 min vs 84±44 min, P<0.001). In patients with ST-segment elevation myocardial infarction, symptoms to first medical contact showed a significant relationship to in-hospital mortality (for every 10 min of symptoms to first medical contact, odds ratio 1.006, 95% confidence interval 1.001-1.012, P=0.018) Conclusions: Circadian and periodic variation in AMI exists in Korean patients, which resulted in different patient behavior, hospital management and outcomes.
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine
Citation
Hyo Eun Park et al. (2010). Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction. Circulation Journal, 74(5), 970–976. doi: 10.1253/circj.CJ-09-0344
Type
Article
ISSN
1346-9843
DOI
10.1253/circj.CJ-09-0344
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35428
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
Authorize & License
  • Authorize공개
Files in This Item:

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.