계명대학교 의학도서관 Repository

Association of cardio-ankle vascular index with diastolic heart function in hypertensive patients

Metadata Downloads
Author(s)
Hyungseop KimHye-Soon KimHyuck-Jun YoonHyoung-Seob ParkYun-Kyeong ChoChang-Wook NamSeung-Ho HurYoon-Nyun KimKwon-Bae Kim
Keimyung Author(s)
Kim, Hyung SeopKim, Hye SoonYoon, Hyuck JunPark, Hyoung SeobCho, Yun KyeongNam, Chang WookHur, Seung HoKim, Yoon NyunKim, Kwon Bae
Department
Dept. of Internal Medicine (내과학)
Journal Title
Clinical and Experimental Hypertension
Issued Date
2014
Volume
36
Issue
4
Abstract
Arterial stiffness is an important risk factor of impaired left ventricular (LV) diastolic function as well as systolic dysfunction. The cardio-ankle vascular index (CAVI) and the ambulatory arterial stiffness index (AASI) can evaluate arteriosclerosis. We analyzed the relationship between arterial stiffness and diastolic function, and then compared the two methodologies to assess which method could serve as a more informative tool for diastology. In total, 136 patients with hypertension underwent 24-h ambulatory blood pressure monitoring (ABPM) and echocardiography including ventricular arterial coupling (VAC). Arterial stiffness was estimated using both CAVI and AASI derived from ABPM. Patients were classified into LV diastolic dysfunction and normal function groups. Those with diastolic dysfunction had a higher CAVI and AASI. Aside from LV torsion, mitral inflow parameters, tissue Doppler velocities and VAC showed a significantly greater association with CAVI, relative to AASI. The receiver operating characteristic curve analysis revealed that CAVI [area under the curve (AUC)===0.869, p=<=0.001] provided significantly more favorable accuracy for diastolic dysfunction compared with AASI (AUC===0.672, p===0.004). Multiple logistic regression analyses showed that CAVI [Odds ratio (OR)===5.1, p===0.009] had a greater association with diastolic dysfunction, relative to age, systolic blood pressure or AASI (OR===1.4, p===0.043). This study indicates that CAVI clinically provides diastolic functional information much better in hypertensive patients than AASI. © 2014 Informa Healthcare USA, Inc. All rights reserved: reproduction in whole or part not permitted.
Keimyung Author(s)(Kor)
김형섭
김혜순
윤혁준
박형섭
조윤경
남창욱
허승호
김윤년
김권배
Publisher
School of Medicine
Citation
Hyungseop Kim et al. (2014). Association of cardio-ankle vascular index with diastolic heart function in hypertensive patients. Clinical and Experimental Hypertension, 36(4), 200–205. doi: 10.3109/10641963.2013.804544
Type
Article
ISSN
1064-1963
Source
https://www.tandfonline.com/doi/full/10.3109/10641963.2013.804544
DOI
10.3109/10641963.2013.804544
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35448
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.